Detailed information NTG0882770

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: QN337_RS09385
• Genome accession: NZ_CP134688
• Coordinates: 1859627..1860529 (+)
• Length: 300 a.a.
• NCBI ID: WP_000912098.1
• Uniprot ID: A0AAD2WWZ7
• Organism: Streptococcus agalactiae strain MA07
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1854627..1865529

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN337_RS09360 (QN337_09355)	purE	1854803..1855294 (+)	492	WP_001875905.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
QN337_RS09365 (QN337_09360)	purK	1855281..1856354 (+)	1074	WP_001048172.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
QN337_RS09370 (QN337_09365)	-	1856364..1856621 (+)	258	WP_000590468.1	hypothetical protein	-
QN337_RS09375 (QN337_09370)	-	1856987..1858090 (+)	1104	WP_001867169.1	DUF6287 domain-containing protein	-
QN337_RS09380 (QN337_09375)	purB	1858176..1859474 (+)	1299	WP_000893937.1	adenylosuccinate lyase	-
QN337_RS09385 (QN337_09380)	comR	1859627..1860529 (+)	903	WP_000912098.1	helix-turn-helix domain-containing protein	Regulator
QN337_RS09390 (QN337_09385)	ruvB	1860818..1861816 (+)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	-
QN337_RS09395 (QN337_09390)	-	1861968..1862405 (+)	438	WP_000754817.1	low molecular weight protein-tyrosine-phosphatase	-
QN337_RS09400 (QN337_09395)	-	1862412..1862792 (+)	381	WP_000787702.1	membrane protein	-
QN337_RS09405 (QN337_09400)	-	1862789..1864567 (+)	1779	WP_001220911.1	acyltransferase family protein	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35606.08 Da
• Isoelectric Point: 6.5030

>NTDB_id=882770 QN337_RS09385 WP_000912098.1 1859627..1860529(+) (comR) [Streptococcus agalactiae strain MA07]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide

• Length: 903 bp

>NTDB_id=882770 QN337_RS09385 WP_000912098.1 1859627..1860529(+) (comR) [Streptococcus agalactiae strain MA07]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-295)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	59.375	96	0.57
comR	Streptococcus mutans UA159	52.174	99.667	0.52
comR	Streptococcus pyogenes MGAS8232	50.166	100	0.503
comR	Streptococcus pyogenes MGAS315	47.667	100	0.477
comR	Streptococcus suis P1/7	40.067	99	0.397
comR	Streptococcus suis 05ZYH33	40.067	99	0.397
comR	Streptococcus suis D9	36.184	100	0.367