Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   RJW51_RS06725 Genome accession   NZ_CP134491
Coordinates   1317650..1319002 (+) Length   450 a.a.
NCBI ID   WP_172090048.1    Uniprot ID   -
Organism   Streptococcus parasuis strain 1628469     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1312650..1324002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW51_RS06715 (RJW51_06700) - 1313720..1314988 (+) 1269 WP_172090050.1 MerR family transcriptional regulator -
  RJW51_RS06720 (RJW51_06705) comA 1315485..1317638 (+) 2154 WP_172090049.1 peptide cleavage/export ABC transporter ComA Regulator
  RJW51_RS06725 (RJW51_06710) comB 1317650..1319002 (+) 1353 WP_172090048.1 bacteriocin secretion accessory protein Regulator
  RJW51_RS06730 (RJW51_06715) - 1319391..1319570 (+) 180 WP_024392853.1 hypothetical protein -
  RJW51_RS06735 (RJW51_06720) - 1319571..1319771 (+) 201 WP_024397558.1 hypothetical protein -
  RJW51_RS06740 (RJW51_06725) - 1319788..1319979 (+) 192 WP_024397557.1 hypothetical protein -
  RJW51_RS06745 (RJW51_06730) - 1320570..1321439 (-) 870 WP_172090047.1 transporter substrate-binding domain-containing protein -
  RJW51_RS06750 (RJW51_06735) - 1321452..1322198 (-) 747 WP_024392849.1 amino acid ABC transporter ATP-binding protein -
  RJW51_RS06755 (RJW51_06740) - 1322203..1322880 (-) 678 WP_024392848.1 amino acid ABC transporter permease -
  RJW51_RS06760 (RJW51_06745) - 1322861..1323550 (-) 690 WP_397610513.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50741.30 Da        Isoelectric Point: 4.7253

>NTDB_id=880380 RJW51_RS06725 WP_172090048.1 1317650..1319002(+) (comB) [Streptococcus parasuis strain 1628469]
MDHHLLESAEFYNRRYHNAASRVIIPSCVLFLFLILFLILAKKEMTISTRATVEPVQRLAQIHSTSNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKVKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCNQLETLASTIDQQN
ATIASQNQAAKQSQLELEKVMHQTEKALADYRELKWAIQSDGVIDEENVGYSIYAQYQLAQSEDAVASQESFVAQIDSQI
SQVETQLASYKLQYAGAGVQQSYTNSLDSQSASLEAQYLTKVGQEMTLLSSQLRELEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLTEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=880380 RJW51_RS06725 WP_172090048.1 1317650..1319002(+) (comB) [Streptococcus parasuis strain 1628469]
ATGGATCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTGTATTGTTTTTGTTTCTCATTCTTTTTTTAATCCTTGCAAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCAGTACAACGATTAGCACAGATTCACTCAACCAGTAATCATCAGATTCTGAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTAGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGGTCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCAATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCTGCAAAACAATCACAATTGGAATTGGAAAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGATTATAGAGAATTGAAATGGGCCATTCAGTCTGATGGCGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGCTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCGTCGCTCAAATCGATAGTCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCTGGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCATTGGAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGAACTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAAACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCAGTTCTAACGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCGAGCATCTCATTAAAGGATAATATCCAATTTT
CAATACAAGGGAAGGGAGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTAATTACAGGTAAGAAGACTTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

49.889

99.778

0.498
  comB Streptococcus pneumoniae D39

47.556

100

0.476
  comB Streptococcus pneumoniae R6

47.556

100

0.476
  comB Streptococcus pneumoniae Rx1

47.556

100

0.476
  comB Streptococcus pneumoniae TIGR4

47.111

100

0.471
  comB Streptococcus mitis NCTC 12261

46.667

100

0.467
  comB Streptococcus mitis SK321

46.222

100

0.462