Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | RJW56_RS06345 | Genome accession | NZ_CP134472 |
| Coordinates | 1300882..1301724 (+) | Length | 280 a.a. |
| NCBI ID | WP_002936492.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain 1522228 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1253034..1338641 | 1300882..1301724 | within | 0 |
Gene organization within MGE regions
Location: 1253034..1338641
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RJW56_RS06115 (RJW56_06115) | - | 1253429..1253653 (+) | 225 | WP_014636996.1 | hypothetical protein | - |
| RJW56_RS06120 (RJW56_06120) | dcm | 1253732..1254934 (+) | 1203 | WP_024394594.1 | DNA (cytosine-5-)-methyltransferase | - |
| RJW56_RS06125 (RJW56_06125) | - | 1254912..1255871 (+) | 960 | WP_024394593.1 | DNA cytosine methyltransferase | - |
| RJW56_RS06130 (RJW56_06130) | - | 1255868..1256320 (+) | 453 | WP_024394592.1 | hypothetical protein | - |
| RJW56_RS06135 (RJW56_06135) | - | 1256339..1256611 (+) | 273 | WP_024394591.1 | hypothetical protein | - |
| RJW56_RS10940 | - | 1258036..1258443 (+) | 408 | WP_225533391.1 | TnpV protein | - |
| RJW56_RS10945 | - | 1259142..1259699 (+) | 558 | Protein_1171 | hypothetical protein | - |
| RJW56_RS06155 (RJW56_06155) | - | 1261486..1262333 (+) | 848 | WP_141669245.1 | IS630 family transposase | - |
| RJW56_RS06160 (RJW56_06160) | - | 1262335..1265438 (+) | 3104 | Protein_1173 | DEAD/DEAH box helicase family protein | - |
| RJW56_RS06165 (RJW56_06165) | - | 1265435..1266076 (+) | 642 | WP_024394509.1 | single-stranded DNA-binding protein | - |
| RJW56_RS06170 (RJW56_06170) | - | 1266155..1266679 (+) | 525 | WP_225533393.1 | CpXC domain-containing protein | - |
| RJW56_RS10950 | - | 1266848..1267018 (+) | 171 | Protein_1176 | recombinase family protein | - |
| RJW56_RS06175 (RJW56_06175) | - | 1267549..1269302 (+) | 1754 | Protein_1177 | beta-glucoside-specific PTS transporter subunit IIABC | - |
| RJW56_RS06180 (RJW56_06180) | ascB | 1269323..1270737 (+) | 1415 | Protein_1178 | 6-phospho-beta-glucosidase | - |
| RJW56_RS06185 (RJW56_06185) | - | 1270815..1271387 (+) | 573 | WP_024394507.1 | DJ-1 family glyoxalase III | - |
| RJW56_RS06190 (RJW56_06190) | - | 1271380..1271937 (+) | 558 | WP_024394506.1 | DJ-1 family glyoxalase III | - |
| RJW56_RS06195 (RJW56_06195) | - | 1271950..1272720 (+) | 771 | WP_024394505.1 | MurR/RpiR family transcriptional regulator | - |
| RJW56_RS06200 (RJW56_06200) | - | 1272758..1273072 (-) | 315 | WP_024394504.1 | DUF5960 family protein | - |
| RJW56_RS06205 (RJW56_06205) | - | 1273059..1273427 (-) | 369 | WP_024394503.1 | hypothetical protein | - |
| RJW56_RS06210 (RJW56_06210) | - | 1273424..1274838 (-) | 1415 | Protein_1184 | Y-family DNA polymerase | - |
| RJW56_RS06215 (RJW56_06215) | - | 1274844..1274978 (-) | 135 | WP_087013866.1 | hypothetical protein | - |
| RJW56_RS06220 (RJW56_06220) | - | 1274981..1275673 (-) | 693 | WP_024394502.1 | XRE family transcriptional regulator | - |
| RJW56_RS06225 (RJW56_06225) | - | 1275837..1276334 (+) | 498 | WP_024394501.1 | hypothetical protein | - |
| RJW56_RS06230 (RJW56_06230) | - | 1276337..1277632 (-) | 1296 | WP_024394500.1 | relaxase/mobilization nuclease domain-containing protein | - |
| RJW56_RS06235 (RJW56_06235) | mobC | 1277634..1277987 (-) | 354 | WP_024394499.1 | plasmid mobilization relaxosome protein MobC | - |
| RJW56_RS06240 (RJW56_06240) | - | 1278170..1278939 (-) | 770 | Protein_1190 | DeoR/GlpR family DNA-binding transcription regulator | - |
| RJW56_RS06245 (RJW56_06245) | - | 1279102..1280499 (+) | 1398 | WP_029750033.1 | rhamnulokinase family protein | - |
| RJW56_RS06250 (RJW56_06250) | - | 1280501..1282288 (+) | 1788 | WP_024394496.1 | L-fucose isomerase | - |
| RJW56_RS06255 (RJW56_06255) | - | 1282302..1282955 (+) | 654 | WP_032532677.1 | L-fuculose-phosphate aldolase | - |
| RJW56_RS06260 (RJW56_06260) | - | 1282975..1284282 (+) | 1308 | WP_024394494.1 | ABC transporter substrate-binding protein | - |
| RJW56_RS06265 (RJW56_06265) | - | 1284341..1285261 (+) | 921 | WP_024394493.1 | carbohydrate ABC transporter permease | - |
| RJW56_RS06270 (RJW56_06270) | - | 1285271..1286110 (+) | 840 | WP_024394492.1 | carbohydrate ABC transporter permease | - |
| RJW56_RS06275 (RJW56_06275) | - | 1286107..1287429 (+) | 1323 | WP_024394491.1 | alpha-L-fucosidase | - |
| RJW56_RS06280 (RJW56_06280) | - | 1287432..1289294 (+) | 1863 | WP_024394490.1 | alpha-N-acetylgalactosaminidase | - |
| RJW56_RS06285 (RJW56_06285) | - | 1289304..1290197 (+) | 894 | WP_024394489.1 | ROK family protein | - |
| RJW56_RS06290 (RJW56_06290) | - | 1290320..1293247 (+) | 2928 | WP_172051284.1 | glycoside hydrolase family 98 domain-containing protein | - |
| RJW56_RS06295 (RJW56_06295) | - | 1293510..1293737 (+) | 228 | WP_023370317.1 | helix-turn-helix domain-containing protein | - |
| RJW56_RS06300 (RJW56_06300) | - | 1294023..1294262 (+) | 240 | WP_004195677.1 | hypothetical protein | - |
| RJW56_RS06305 (RJW56_06305) | - | 1294352..1295872 (+) | 1521 | WP_024394487.1 | tyrosine-type recombinase/integrase | - |
| RJW56_RS06310 (RJW56_06310) | ylqF | 1295964..1296815 (+) | 852 | WP_024394486.1 | ribosome biogenesis GTPase YlqF | - |
| RJW56_RS06315 (RJW56_06315) | - | 1296802..1297575 (+) | 774 | WP_024387771.1 | ribonuclease HII | - |
| RJW56_RS06320 (RJW56_06320) | - | 1297578..1298588 (+) | 1011 | WP_029174502.1 | YdcF family protein | - |
| RJW56_RS06325 (RJW56_06325) | - | 1298621..1299271 (-) | 651 | WP_002936498.1 | hemolysin III family protein | - |
| RJW56_RS06330 (RJW56_06330) | - | 1299261..1299812 (-) | 552 | WP_024394485.1 | DUF1836 domain-containing protein | - |
| RJW56_RS06335 (RJW56_06335) | - | 1299909..1300220 (-) | 312 | WP_014637902.1 | rhodanese-like domain-containing protein | - |
| RJW56_RS06340 (RJW56_06340) | - | 1300362..1300823 (+) | 462 | Protein_1210 | sugar O-acetyltransferase | - |
| RJW56_RS06345 (RJW56_06345) | dprA | 1300882..1301724 (+) | 843 | WP_002936492.1 | DNA-processing protein DprA | Machinery gene |
| RJW56_RS06350 (RJW56_06350) | topA | 1301817..1303910 (+) | 2094 | WP_024394484.1 | type I DNA topoisomerase | - |
| RJW56_RS06355 (RJW56_06355) | rplJ | 1304487..1304981 (+) | 495 | WP_002936486.1 | 50S ribosomal protein L10 | - |
| RJW56_RS06360 (RJW56_06360) | rplL | 1305047..1305412 (+) | 366 | WP_002936483.1 | 50S ribosomal protein L7/L12 | - |
| RJW56_RS06365 (RJW56_06365) | - | 1305612..1305785 (+) | 174 | WP_002936480.1 | hypothetical protein | - |
| RJW56_RS06370 (RJW56_06370) | - | 1305782..1306600 (+) | 819 | WP_002936477.1 | replication initiator protein A | - |
| RJW56_RS06375 (RJW56_06375) | dcm | 1306749..1308104 (+) | 1356 | WP_002936475.1 | DNA (cytosine-5-)-methyltransferase | - |
| RJW56_RS06380 (RJW56_06380) | - | 1308088..1308516 (+) | 429 | WP_002936474.1 | hypothetical protein | - |
| RJW56_RS06385 (RJW56_06385) | - | 1308527..1308910 (+) | 384 | WP_002936473.1 | hypothetical protein | - |
| RJW56_RS06390 (RJW56_06390) | - | 1308919..1309152 (+) | 234 | WP_002935120.1 | hypothetical protein | - |
| RJW56_RS06395 (RJW56_06395) | - | 1309155..1309740 (+) | 586 | Protein_1221 | CPBP family intramembrane glutamic endopeptidase | - |
| RJW56_RS06400 (RJW56_06400) | - | 1309818..1310306 (+) | 489 | WP_024397125.1 | hypothetical protein | - |
| RJW56_RS06405 (RJW56_06405) | - | 1310306..1312123 (+) | 1818 | WP_002936459.1 | VirD4-like conjugal transfer protein, CD1115 family | - |
| RJW56_RS06410 (RJW56_06410) | - | 1312141..1312383 (+) | 243 | WP_001072171.1 | hypothetical protein | - |
| RJW56_RS06415 (RJW56_06415) | - | 1312402..1313256 (+) | 855 | WP_012775518.1 | conjugal transfer protein TrbL | - |
| RJW56_RS06420 (RJW56_06420) | - | 1313318..1313671 (+) | 354 | WP_001097579.1 | PrgI family protein | - |
| RJW56_RS06425 (RJW56_06425) | - | 1313628..1315979 (+) | 2352 | WP_029749990.1 | VirB4-like conjugal transfer ATPase, CD1110 family | - |
| RJW56_RS06430 (RJW56_06430) | - | 1315981..1318782 (+) | 2802 | WP_172051304.1 | phage tail tip lysozyme | - |
| RJW56_RS06435 (RJW56_06435) | - | 1318919..1319929 (+) | 1011 | WP_002936451.1 | Abi family protein | - |
| RJW56_RS06440 (RJW56_06440) | - | 1320271..1325166 (+) | 4896 | WP_311063468.1 | SspB-related isopeptide-forming adhesin | - |
| RJW56_RS06445 (RJW56_06445) | - | 1325167..1325358 (+) | 192 | WP_001068448.1 | calcium-binding protein | - |
| RJW56_RS06450 (RJW56_06450) | - | 1325342..1325893 (+) | 552 | WP_002936438.1 | hypothetical protein | - |
| RJW56_RS06455 (RJW56_06455) | - | 1325943..1331846 (+) | 5904 | WP_311063470.1 | SNF2-related protein | - |
| RJW56_RS06460 (RJW56_06460) | ltrA | 1332411..1334222 (+) | 1812 | WP_002936434.1 | group II intron reverse transcriptase/maturase | - |
| RJW56_RS06465 (RJW56_06465) | - | 1334327..1335274 (+) | 948 | Protein_1235 | hypothetical protein | - |
| RJW56_RS06470 (RJW56_06470) | - | 1335345..1335644 (+) | 300 | WP_024401832.1 | DUF5962 family protein | - |
| RJW56_RS06475 (RJW56_06475) | - | 1335658..1335948 (+) | 291 | WP_024394788.1 | DUF5966 family protein | - |
| RJW56_RS06480 (RJW56_06480) | - | 1336044..1336671 (+) | 628 | Protein_1238 | peptidylprolyl isomerase | - |
| RJW56_RS06485 (RJW56_06485) | - | 1336719..1337093 (+) | 375 | WP_001129922.1 | TnpV protein | - |
Sequence
Protein
Download Length: 280 a.a. Molecular weight: 31261.11 Da Isoelectric Point: 8.4451
>NTDB_id=880119 RJW56_RS06345 WP_002936492.1 1300882..1301724(+) (dprA) [Streptococcus suis strain 1522228]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAIVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAIVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF
Nucleotide
Download Length: 843 bp
>NTDB_id=880119 RJW56_RS06345 WP_002936492.1 1300882..1301724(+) (dprA) [Streptococcus suis strain 1522228]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTATAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCGCCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
TGCAGTCGTTGGTACACGAAATGCCAGCAAAAATGGTATTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCTCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCTGTAATTGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATCGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGAAATCGCATCATTGCTGGGTTGG
TAGAAGGATTGGTAGTCTGTGAGGCTAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTATAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCGCCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
TGCAGTCGTTGGTACACGAAATGCCAGCAAAAATGGTATTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCTCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCTGTAATTGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATCGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGAAATCGCATCATTGCTGGGTTGG
TAGAAGGATTGGTAGTCTGTGAGGCTAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Streptococcus mutans UA159 |
69.286 |
100 |
0.693 |
| dprA/cilB/dalA | Streptococcus pneumoniae Rx1 |
63.571 |
100 |
0.636 |
| dprA/cilB/dalA | Streptococcus pneumoniae D39 |
63.571 |
100 |
0.636 |
| dprA/cilB/dalA | Streptococcus pneumoniae R6 |
63.571 |
100 |
0.636 |
| dprA/cilB/dalA | Streptococcus pneumoniae TIGR4 |
63.571 |
100 |
0.636 |
| dprA/cilB/dalA | Streptococcus mitis SK321 |
63.571 |
100 |
0.636 |
| dprA/cilB/dalA | Streptococcus mitis NCTC 12261 |
63.571 |
100 |
0.636 |
| dprA | Lactococcus lactis subsp. cremoris KW2 |
60.357 |
100 |
0.604 |
| dprA | Legionella pneumophila strain ERS1305867 |
41.7 |
88.214 |
0.368 |
| dprA | Bacillus subtilis subsp. subtilis str. 168 |
50.746 |
71.786 |
0.364 |