Detailed information NTG0877775

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: RIM63_RS07845
• Genome accession: NZ_CP133952
• Coordinates: 1634186..1636342 (+)
• Length: 718 a.a.
• NCBI ID: WP_317583713.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain HT321
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1629186..1641342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIM63_RS07805 (RIM63_07805)	-	1629616..1630196 (-)	581	Protein_1513	GNAT family N-acetyltransferase	-
RIM63_RS07810 (RIM63_07810)	-	1630453..1630866 (-)	414	WP_014623333.1	hypothetical protein	-
RIM63_RS07815 (RIM63_07815)	-	1631518..1631721 (-)	204	WP_012679939.1	bacteriocin	-
RIM63_RS07820 (RIM63_07820)	-	1631739..1631993 (-)	255	WP_111692691.1	Blp family class II bacteriocin	-
RIM63_RS07825 (RIM63_07825)	-	1632145..1632441 (-)	297	WP_317583708.1	bacteriocin immunity protein	-
RIM63_RS07830 (RIM63_07830)	-	1632441..1632659 (-)	219	WP_037579371.1	leucocin A/sakacin P family class II bacteriocin	-
RIM63_RS07835 (RIM63_07835)	-	1633376..1633672 (-)	297	WP_111692935.1	bacteriocin immunity protein	-
RIM63_RS07840 (RIM63_07840)	-	1633679..1633927 (-)	249	WP_111692693.1	garvicin Q family class II bacteriocin	-
RIM63_RS07845 (RIM63_07845)	comA/nlmT	1634186..1636342 (+)	2157	WP_317583713.1	peptide cleavage/export ABC transporter	Regulator
RIM63_RS07850 (RIM63_07850)	-	1636353..1637711 (+)	1359	WP_317583715.1	bacteriocin secretion accessory protein	-
RIM63_RS07855 (RIM63_07855)	-	1637811..1637945 (+)	135	WP_012516117.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
RIM63_RS07860 (RIM63_07860)	-	1638063..1639193 (-)	1131	WP_317583717.1	GHKL domain-containing protein	-
RIM63_RS07865 (RIM63_07865)	comE/blpR	1639386..1640135 (-)	750	WP_317583718.1	response regulator transcription factor	Regulator
RIM63_RS07870 (RIM63_07870)	-	1640781..1640984 (-)	204	WP_012516120.1	TmhB bacteriocin enhancer peptide	-
RIM63_RS07875 (RIM63_07875)	-	1641001..1641246 (-)	246	WP_317583720.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 80556.79 Da
• Isoelectric Point: 7.7838

>NTDB_id=877775 RIM63_RS07845 WP_317583713.1 1634186..1636342(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain HT321]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEIGFETKPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
LIICAFIKPFEQMNHDVMQSNAMLNSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEVVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYVFNGSILENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide

• Length: 2157 bp

>NTDB_id=877775 RIM63_RS07845 WP_317583713.1 1634186..1636342(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATAGGGTTTGAAACCAAACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAT
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGTCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCA
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGCTGGTTC
ATACTATCTCCAGGGGATTTTAGACGAGTATATTCCAAATCAACTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCCTCAACCATTTTATCTCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTGTCCCTGATTTCTATTCCAGTATATACC
CTTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAACTCTGC
TATTATCGAAGATATCAATGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTTGATAAGTCTTTTAAGCTTAGTAAATATACCATCTTACAAGCCACCCTCAAGCAAGGAGCGCAG
CTGATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTCATTAATGGTAAAATTTCAATCGGGCAATTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAATCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGTTGTTTCCTATAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAGCCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATGTGTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAGGGCAT
CAGCCAGGAAGACATTCTTAAAGCCTGTGAGATTGCTGATATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAACTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTTGTTCTTAATCAAG
GGCAAATCATTGAGACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (8-143)

• ABC transporter (ABC_tran) (501-650)

• ABC transporter transmembrane region (ABC_membrane) (169-439)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.851	99.861	0.708
comA	Streptococcus mitis SK321	67.742	99.304	0.673
comA	Streptococcus mitis NCTC 12261	67.461	99.304	0.67
comA	Streptococcus pneumoniae Rx1	67.041	99.304	0.666
comA	Streptococcus pneumoniae D39	67.041	99.304	0.666
comA	Streptococcus pneumoniae R6	67.041	99.304	0.666
comA	Streptococcus pneumoniae TIGR4	66.76	99.304	0.663
comA	Streptococcus gordonii str. Challis substr. CH1	65.358	99.304	0.649