Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   RIM63_RS07865 Genome accession   NZ_CP133952
Coordinates   1639386..1640135 (-) Length   249 a.a.
NCBI ID   WP_317583718.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain HT321     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1634386..1645135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIM63_RS07850 (RIM63_07850) - 1636353..1637711 (+) 1359 WP_317583715.1 bacteriocin secretion accessory protein -
  RIM63_RS07855 (RIM63_07855) - 1637811..1637945 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  RIM63_RS07860 (RIM63_07860) - 1638063..1639193 (-) 1131 WP_317583717.1 GHKL domain-containing protein -
  RIM63_RS07865 (RIM63_07865) comE/blpR 1639386..1640135 (-) 750 WP_317583718.1 response regulator transcription factor Regulator
  RIM63_RS07870 (RIM63_07870) - 1640781..1640984 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  RIM63_RS07875 (RIM63_07875) - 1641001..1641246 (-) 246 WP_317583720.1 Blp family class II bacteriocin -
  RIM63_RS07880 (RIM63_07880) rlmD 1641567..1642934 (-) 1368 WP_317583722.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  RIM63_RS07885 (RIM63_07885) - 1642931..1643899 (-) 969 WP_317583725.1 DNA-binding protein -
  RIM63_RS07890 (RIM63_07890) recX 1643963..1644739 (+) 777 WP_111678367.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29150.67 Da        Isoelectric Point: 8.3390

>NTDB_id=877776 RIM63_RS07865 WP_317583718.1 1639386..1640135(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain HT321]
MRVVILEDDMIQQRCLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFRYQVSALDYIDKELPHIEFVQRVEAALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNIVRVDKTERVVYFRNGSSCLIARSKMNSVLAT
IENLHRGDD

Nucleotide


Download         Length: 750 bp        

>NTDB_id=877776 RIM63_RS07865 WP_317583718.1 1639386..1640135(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain HT321]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAACAGAGATGTTTAGAAAAGCTTATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGATTGTTTTGGAAGGCCTCACCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGATAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTAGCTTTTCGGTATCAAGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACATTGAGTTTGTTCAACGGGTAGAGGCTGCCTTATTATATGCTGTGCGACAAAATA
GTGAAACTATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACGGGGACTTTGACGGA
TATTTTAAAGCAAGAGTCTCGTTTTTTGCAATGTCACCGTTCTTTTTTGATTAATCCTAGGAATATCGTTAGGGTGGATA
AGACTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAGCAACA
ATTGAGAACCTGCATAGAGGAGATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.012

100

0.53
  comE/comE1 Streptococcus equinus JB1

39.749

95.984

0.382
  comE/comE2 Streptococcus equinus JB1

37.19

97.189

0.361