Detailed information NTG0877762

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: RIM63_RS04875
• Genome accession: NZ_CP133952
• Coordinates: 1010926..1011600 (+)
• Length: 224 a.a.
• NCBI ID: WP_037578348.1
• Uniprot ID: A0A922NWP3
• Organism: Streptococcus equi subsp. zooepidemicus strain HT321
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1005926..1016600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIM63_RS04860 (RIM63_04860)	pstB	1006252..1007010 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
RIM63_RS04865 (RIM63_04865)	phoU	1007081..1007734 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
RIM63_RS04870 (RIM63_04870)	-	1007968..1010505 (+)	2538	WP_206158612.1	M1 family metallopeptidase	-
RIM63_RS04875 (RIM63_04875)	ciaR	1010926..1011600 (+)	675	WP_037578348.1	response regulator transcription factor	Regulator
RIM63_RS04880 (RIM63_04880)	ciaH	1011593..1012903 (+)	1311	WP_317585160.1	HAMP domain-containing sensor histidine kinase	Regulator
RIM63_RS04885 (RIM63_04885)	-	1013288..1013716 (+)	429	WP_317585162.1	hypothetical protein	-
RIM63_RS04890 (RIM63_04890)	-	1013943..1014338 (+)	396	WP_115250909.1	DUF1433 domain-containing protein	-
RIM63_RS04895 (RIM63_04895)	-	1014338..1014583 (+)	246	WP_317585164.1	hypothetical protein	-
RIM63_RS04900 (RIM63_04900)	-	1014602..1015000 (+)	399	WP_231871354.1	hypothetical protein	-
RIM63_RS04905 (RIM63_04905)	-	1015003..1016196 (+)	1194	WP_317585168.1	hypothetical protein	-
RIM63_RS04910 (RIM63_04910)	-	1016193..1016585 (+)	393	WP_317583847.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25555.55 Da
• Isoelectric Point: 4.5644

>NTDB_id=877762 RIM63_RS04875 WP_037578348.1 1010926..1011600(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain HT321]
MIKILLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=877762 RIM63_RS04875 WP_037578348.1 1010926..1011600(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGATAAAAATATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTAATGC
TGCCTGAAAAGGATGGCTTTCAGGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACTCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGTAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	81.448	98.661	0.804
ciaR	Streptococcus pneumoniae D39	81.448	98.661	0.804
ciaR	Streptococcus pneumoniae R6	81.448	98.661	0.804
ciaR	Streptococcus pneumoniae TIGR4	81.448	98.661	0.804
covR	Lactococcus lactis subsp. lactis strain DGCC12653	39.301	100	0.402
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.362