Detailed information NTG0877613

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: RIM62_RS00300
• Genome accession: NZ_CP133950
• Coordinates: 50677..51591 (+)
• Length: 304 a.a.
• NCBI ID: WP_043030321.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain ZHZ211
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45677..56591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIM62_RS00275 (RIM62_00275)	purE	46842..47330 (+)	489	WP_159334807.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
RIM62_RS00280 (RIM62_00280)	purK	47317..48408 (+)	1092	WP_159334808.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
RIM62_RS00285 (RIM62_00285)	-	48418..48642 (+)	225	WP_012514713.1	hypothetical protein	-
RIM62_RS00290 (RIM62_00290)	-	48666..48770 (+)	105	WP_370444775.1	hypothetical protein	-
RIM62_RS00295 (RIM62_00295)	purB	49087..50379 (+)	1293	WP_037582405.1	adenylosuccinate lyase	-
RIM62_RS00300 (RIM62_00300)	comR	50677..51591 (+)	915	WP_043030321.1	XRE family transcriptional regulator	Regulator
RIM62_RS10465	comS	51674..51772 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
RIM62_RS00305 (RIM62_00305)	ruvB	51806..52807 (+)	1002	WP_115266532.1	Holliday junction branch migration DNA helicase RuvB	-
RIM62_RS00310 (RIM62_00310)	-	53055..53513 (+)	459	WP_012678781.1	low molecular weight protein-tyrosine-phosphatase	-
RIM62_RS00315 (RIM62_00315)	-	53519..53920 (+)	402	WP_115266533.1	MORN repeat-containing protein	-
RIM62_RS00320 (RIM62_00320)	-	53917..55698 (+)	1782	WP_111689737.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35818.40 Da
• Isoelectric Point: 4.5517

>NTDB_id=877613 RIM62_RS00300 WP_043030321.1 50677..51591(+) (comR) [Streptococcus equi subsp. zooepidemicus strain ZHZ211]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=877613 RIM62_RS00300 WP_043030321.1 50677..51591(+) (comR) [Streptococcus equi subsp. zooepidemicus strain ZHZ211]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAGTTATCCATCCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAACTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGATTGCTTACAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAGCAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_19) (6-69)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.587	99.671	0.743
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis P1/7	38.255	98.026	0.375
comR	Streptococcus suis D9	37.542	99.013	0.372
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372