Detailed information NTG0874448

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: WJ062_RS07120
• Genome accession: NZ_CP149486
• Coordinates: 1457999..1460827 (-)
• Length: 942 a.a.
• NCBI ID: WP_021340890.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain EMM113
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1452999..1465827

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WJ062_RS07090 (WJ062_07060)	-	1453675..1454640 (+)	966	WP_002988504.1	LacI family DNA-binding transcriptional regulator	-
WJ062_RS07095 (WJ062_07065)	nusB	1454781..1455233 (-)	453	WP_002988501.1	transcription antitermination factor NusB	-
WJ062_RS07100 (WJ062_07070)	-	1455226..1455615 (-)	390	WP_002983163.1	Asp23/Gls24 family envelope stress response protein	-
WJ062_RS07105 (WJ062_07075)	efp	1455661..1456218 (-)	558	WP_002988496.1	elongation factor P	-
WJ062_RS07110 (WJ062_07080)	-	1456314..1456775 (-)	462	WP_002988493.1	deaminase	-
WJ062_RS07115 (WJ062_07085)	-	1456810..1457883 (-)	1074	WP_002988490.1	Xaa-Pro peptidase family protein	-
WJ062_RS07120 (WJ062_07090)	uvrA	1457999..1460827 (-)	2829	WP_021340890.1	excinuclease ABC subunit UvrA	Machinery gene
WJ062_RS07125 (WJ062_07095)	-	1461030..1461974 (+)	945	WP_002983147.1	magnesium transporter CorA family protein	-
WJ062_RS07130 (WJ062_07100)	-	1462106..1462762 (+)	657	WP_002983144.1	DUF1129 domain-containing protein	-
WJ062_RS07135 (WJ062_07105)	rpsR	1462895..1463134 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
WJ062_RS07140 (WJ062_07110)	ssb	1463299..1463790 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
WJ062_RS07145 (WJ062_07115)	rpsF	1463812..1464102 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
WJ062_RS07150 (WJ062_07120)	-	1464275..1464568 (-)	294	WP_002983113.1	hypothetical protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104062.23 Da
• Isoelectric Point: 6.0690

>NTDB_id=874448 WJ062_RS07120 WP_021340890.1 1457999..1460827(-) (uvrA) [Streptococcus pyogenes strain EMM113]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVIYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=874448 WJ062_RS07120 WP_021340890.1 1457999..1460827(-) (uvrA) [Streptococcus pyogenes strain EMM113]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTCGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTTACGGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGTTATGTCCGTGTGCGGGTTGACGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCCAAAAGTAAGATGCACAACATCGAGGTGGTTATTGACCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGGTTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGAGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGATATTCCTTTTG
AAGGTGTTGTGACTAATGTTAATCGTCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGTTATATG
AACGAATTGACCTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAATTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTGTCACGGGCTGCTGGGACTTTATCAGGTGGTGAAAGTCAACGAATCAGGTTAGCGACACAAATTGGTTCTAACTT
ATCAGGGGTGATCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGGCCTGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCGCAGAATAATCTTCAAAGCCTCGACGTGAGATTCCCACTGGGTAAATTTATTGCGGTCACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGCTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTACTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCCACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA interaction domain (UvrA_inter) (132-238)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.82	100	0.848
uvrA	Streptococcus pneumoniae TIGR4	84.82	100	0.848
uvrA	Streptococcus pneumoniae D39	84.82	100	0.848