Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   Q7609_RS03010 Genome accession   NZ_CP131725
Coordinates   606134..607477 (+) Length   447 a.a.
NCBI ID   WP_342123374.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018S05-172     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 601134..612477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7609_RS02985 (Q7609_02985) - 601193..603793 (-) 2601 WP_342123371.1 penicillin-binding protein 1A -
  Q7609_RS02990 (Q7609_02990) comA 603892..604689 (+) 798 WP_116965314.1 competence protein ComA Machinery gene
  Q7609_RS02995 (Q7609_02995) comB 604690..605196 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  Q7609_RS03000 (Q7609_03000) comC 605193..605714 (+) 522 WP_342123372.1 competence protein ComC Machinery gene
  Q7609_RS03005 (Q7609_03005) comD 605711..606124 (+) 414 WP_342123373.1 pilus assembly protein PilP Machinery gene
  Q7609_RS03010 (Q7609_03010) comE 606134..607477 (+) 1344 WP_342123374.1 type IV pilus secretin PilQ Machinery gene
  Q7609_RS03015 (Q7609_03015) tnpA 607474..607929 (+) 456 WP_005652127.1 IS200/IS605 family transposase -
  Q7609_RS03020 (Q7609_03020) - 608301..608987 (+) 687 WP_005652129.1 ComF family protein -
  Q7609_RS03025 (Q7609_03025) nfuA 609063..609659 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  Q7609_RS03030 (Q7609_03030) nudC 609726..610520 (+) 795 WP_014550416.1 NAD(+) diphosphatase -
  Q7609_RS03035 (Q7609_03035) - 610556..611146 (+) 591 WP_005656455.1 YjaG family protein -
  Q7609_RS03040 (Q7609_03040) - 611286..611558 (+) 273 WP_014550417.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49394.69 Da        Isoelectric Point: 7.9388

>NTDB_id=864865 Q7609_RS03010 WP_342123374.1 606134..607477(+) (comE) [Haemophilus influenzae strain 2018S05-172]
MKKYLLKRGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSSKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTKGSGSLLSSAGSITFDDRSN
LLVIQDDPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGIRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTATPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=864865 Q7609_RS03010 WP_342123374.1 606134..607477(+) (comE) [Haemophilus influenzae strain 2018S05-172]
ATGAAGAAATATCTTTTAAAGCGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACATTGGAACAATTGGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAAGCAAAGG
TCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACCTAGTGAGTCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGAAAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGATCCTCGTTCTGTGCAAAATATTAAAAAACTAATTGCTGAAATGGATAAACCTATTGAGCA
GATCGCTATTGAAGCGCGAATTGTGACGATAACCGATGAGAGTTTGAAAGAACTTGGTATTCGCTGGGGGATTTTTAATC
CAACGGAAAATGCAAGACGAGTTGCGGGCAGTCTTGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACAGCGACACCTGCTGGCTCGATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTCGATTTAGAATT
AAGCGCGTTAGAGCGTGAAAATAATGTGGAAATTATCGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTATGTTGTGAGCAATACTCGTAACGATACACAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAACAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCTGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTCACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

95.281

99.553

0.949
  comE Haemophilus influenzae Rd KW20

95.056

99.553

0.946
  comE Glaesserella parasuis strain SC1401

52.706

95.078

0.501
  pilQ Vibrio campbellii strain DS40M4

42.721

93.736

0.4
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.928

92.841

0.389
  pilQ Vibrio cholerae strain A1552

41.928

92.841

0.389