Detailed information NTG0864068

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: Q7624_RS09780
• Genome accession: NZ_CP131709
• Coordinates: 1882574..1883035 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250545.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2016S11-245
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1877574..1888035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7624_RS09745 (Q7624_09720)	-	1877885..1878709 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
Q7624_RS09750 (Q7624_09725)	rnpA	1878684..1879055 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7624_RS09755 (Q7624_09730)	-	1879072..1879203 (-)	132	WP_000768904.1	hypothetical protein	-
Q7624_RS09760 (Q7624_09735)	-	1879204..1880394 (-)	1191	WP_000167766.1	acetate kinase	-
Q7624_RS09765 (Q7624_09740)	comYH	1880445..1881398 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
Q7624_RS09770 (Q7624_09745)	-	1881459..1882046 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
Q7624_RS09775 (Q7624_09750)	comGG/cglG	1882183..1882596 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7624_RS09780 (Q7624_09755)	comGF/cglF	1882574..1883035 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7624_RS09785 (Q7624_09760)	comGE/cglE	1882998..1883300 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7624_RS09790 (Q7624_09765)	comGD/cglD	1883263..1883667 (-)	405	WP_061763003.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7624_RS09795 (Q7624_09770)	comGC/cglC	1883660..1883986 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
Q7624_RS09800 (Q7624_09775)	comGB/cglB	1883988..1885004 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7624_RS09805 (Q7624_09780)	comGA/cglA/cilD	1884952..1885893 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7624_RS09810 (Q7624_09785)	-	1885969..1886334 (-)	366	WP_000286415.1	DUF1033 family protein	-
Q7624_RS09815 (Q7624_09790)	-	1886485..1887543 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17855.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=864068 Q7624_RS09780 WP_000250545.1 1882574..1883035(-) (comGF/cglF) [Streptococcus pneumoniae strain 2016S11-245]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=864068 Q7624_RS09780 WP_000250545.1 1882574..1883035(-) (comGF/cglF) [Streptococcus pneumoniae strain 2016S11-245]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915