NTDB

Overview

Name	comGE/cglE	Type	Machinery gene
Locus tag	Q7624_RS09785	Genome accession	NZ_CP131709
Coordinates	1882998..1883300 (-)	Length	100 a.a.
NCBI ID	WP_000413380.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain 2016S11-245
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1877998..1888300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7624_RS09750 (Q7624_09725)	rnpA	1878684..1879055 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7624_RS09755 (Q7624_09730)	-	1879072..1879203 (-)	132	WP_000768904.1	hypothetical protein	-
Q7624_RS09760 (Q7624_09735)	-	1879204..1880394 (-)	1191	WP_000167766.1	acetate kinase	-
Q7624_RS09765 (Q7624_09740)	comYH	1880445..1881398 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
Q7624_RS09770 (Q7624_09745)	-	1881459..1882046 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
Q7624_RS09775 (Q7624_09750)	comGG/cglG	1882183..1882596 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7624_RS09780 (Q7624_09755)	comGF/cglF	1882574..1883035 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7624_RS09785 (Q7624_09760)	comGE/cglE	1882998..1883300 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7624_RS09790 (Q7624_09765)	comGD/cglD	1883263..1883667 (-)	405	WP_061763003.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7624_RS09795 (Q7624_09770)	comGC/cglC	1883660..1883986 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
Q7624_RS09800 (Q7624_09775)	comGB/cglB	1883988..1885004 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7624_RS09805 (Q7624_09780)	comGA/cglA/cilD	1884952..1885893 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7624_RS09810 (Q7624_09785)	-	1885969..1886334 (-)	366	WP_000286415.1	DUF1033 family protein	-
Q7624_RS09815 (Q7624_09790)	-	1886485..1887543 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

Download Length: 100 a.a. Molecular weight: 11135.11 Da Isoelectric Point: 9.7273

                                >NTDB_id=864069 Q7624_RS09785 WP_000413380.1 1882998..1883300(-) (comGE/cglE) [Streptococcus pneumoniae strain 2016S11-245]

MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS

SEKGLEVYHGSEQLLAIKEP

Nucleotide

Download Length: 303 bp

                                >NTDB_id=864069 Q7624_RS09785 WP_000413380.1 1882998..1883300(-) (comGE/cglE) [Streptococcus pneumoniae strain 2016S11-245]

ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT

TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG

TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT

AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39

Detailed information NTG0864069