Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   Q7626_RS09790 Genome accession   NZ_CP131707
Coordinates   1911197..1912213 (-) Length   338 a.a.
NCBI ID   WP_012512625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2018C08-270     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1906197..1917213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7626_RS09745 (Q7626_09730) - 1906274..1906405 (-) 132 WP_000768904.1 hypothetical protein -
  Q7626_RS09750 (Q7626_09735) - 1906406..1907596 (-) 1191 WP_000167766.1 acetate kinase -
  Q7626_RS09755 (Q7626_09740) comYH 1907647..1908600 (-) 954 WP_000345101.1 class I SAM-dependent methyltransferase Machinery gene
  Q7626_RS09760 (Q7626_09745) - 1908661..1909255 (-) 595 Protein_1897 methyltransferase domain-containing protein -
  Q7626_RS09765 (Q7626_09750) comGG/cglG 1909392..1909805 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  Q7626_RS09770 (Q7626_09755) comGF/cglF 1909783..1910244 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  Q7626_RS09775 (Q7626_09760) comGE/cglE 1910207..1910509 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  Q7626_RS09780 (Q7626_09765) comGD/cglD 1910472..1910876 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  Q7626_RS09785 (Q7626_09770) comGC/cglC 1910869..1911195 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  Q7626_RS09790 (Q7626_09775) comGB/cglB 1911197..1912213 (-) 1017 WP_012512625.1 competence type IV pilus assembly protein ComGB Machinery gene
  Q7626_RS09795 (Q7626_09780) comGA/cglA/cilD 1912161..1913102 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  Q7626_RS09800 (Q7626_09785) - 1913178..1913543 (-) 366 WP_000286415.1 DUF1033 family protein -
  Q7626_RS09805 (Q7626_09790) - 1913694..1914752 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  Q7626_RS09810 (Q7626_09795) nagA 1914915..1916066 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38524.56 Da        Isoelectric Point: 9.6162

>NTDB_id=863919 Q7626_RS09790 WP_012512625.1 1911197..1912213(-) (comGB/cglB) [Streptococcus pneumoniae strain 2018C08-270]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LVMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=863919 Q7626_RS09790 WP_012512625.1 1911197..1912213(-) (comGB/cglB) [Streptococcus pneumoniae strain 2018C08-270]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGTCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

57.595

93.491

0.538
  comYB Streptococcus mutans UA159

57.595

93.491

0.538
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503