Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   STYK_RS00285 Genome accession   NZ_AP024523
Coordinates   53049..54398 (+) Length   449 a.a.
NCBI ID   WP_049551500.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 48049..59398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS00255 (STYK_00440) - 49250..49447 (+) 198 WP_084923534.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  STYK_RS00265 (STYK_00460) - 49661..49816 (+) 156 WP_000357248.1 smi_0061 family bacteriocin-like peptide -
  STYK_RS00270 (STYK_00470) - 49820..50035 (+) 216 WP_080550793.1 bacteriocin immunity protein -
  STYK_RS00275 (STYK_00480) - 50116..50295 (+) 180 WP_000846993.1 hypothetical protein -
  STYK_RS00280 (STYK_00490) comA 50883..53036 (+) 2154 WP_261805017.1 peptide cleavage/export ABC transporter ComA Regulator
  STYK_RS00285 (STYK_00500) comB 53049..54398 (+) 1350 WP_049551500.1 competence pheromone export protein ComB Regulator
  STYK_RS00290 (STYK_00510) purC 54569..55276 (+) 708 WP_142358187.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  STYK_RS10240 - 55278..55421 (+) 144 WP_315972287.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  STYK_RS00295 (STYK_00520) - 55478..59203 (+) 3726 WP_261805018.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49799.71 Da        Isoelectric Point: 5.3945

>NTDB_id=85708 STYK_RS00285 WP_049551500.1 53049..54398(+) (comB) [Streptococcus toyakuensis strain TP1632]
MKPEFLESAEFYNRRYHNFSSRVIVPMFLLLVFLLGFATLAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQSKAQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGALLAQLYPSLEKEGQAKLTAYLSSKDVARIKVGDSVRYTTTHDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=85708 STYK_RS00285 WP_049551500.1 53049..54398(+) (comB) [Streptococcus toyakuensis strain TP1632]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTGCCCAT
GTTCCTTCTGCTCGTGTTTTTGCTTGGCTTTGCAACTTTGGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTGTAG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGTAACAATCGCATTCTTGTCAATCATCTGGAAGAAAATAAGCTG
GTTAAAAAGGGGGATCTTTTGGTTCAATACCAGGAAGGGGCAGAGGGTGTCCAAGCGGAGGCCTATGCTAGTCAGTTGGA
CATGCTCAAGGATCAGAAAAAGCAATTGGAGTATTTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATTGCATCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGCCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCCTATAAGTCTCAGGGCGAGGAAAATCCGCAATCTAAGGCTCAGGCTGTTGCTCAGGTAGAAGCACAGCTCTCT
CAGTTAGAATCCAGTCTTGCTACTTACCGTGTTCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCTGGTTTAAG
TAGTCAATTAGAGTCCCTTAAATCCCAACATTTGGCTAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATTTTGG
AGGCAGAATCGGGTAAGAAGGTTCAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCTAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGATTCTACCATGGTAGCAGAAGGCGCCTTACTAGCCCAACTCTATCCGTCCTTGGAAAAAGA
AGGGCAAGCCAAACTAACAGCTTATCTTAGTTCAAAAGATGTAGCAAGGATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCAAGAATCAAATTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAAAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTCGGTACGGGGTGGAAGGTCG
CCTGCAGATGATTACGGGCAAGAAAAGTTACCTGCGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

97.105

100

0.971
  comB Streptococcus mitis NCTC 12261

96.882

100

0.969
  comB Streptococcus pneumoniae TIGR4

96.437

100

0.964
  comB Streptococcus pneumoniae D39

96.214

100

0.962
  comB Streptococcus pneumoniae Rx1

96.214

100

0.962
  comB Streptococcus pneumoniae R6

96.214

100

0.962
  comB Streptococcus gordonii str. Challis substr. CH1

55.556

100

0.557

Multiple sequence alignment