Detailed information NTG0085707

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: STYK_RS00280
• Genome accession: NZ_AP024523
• Coordinates: 50883..53036 (+)
• Length: 717 a.a.
• NCBI ID: WP_261805017.1
• Uniprot ID: -
• Organism: Streptococcus toyakuensis strain TP1632
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 45883..58036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STYK_RS00240 (STYK_00400)	-	46335..46469 (+)	135	WP_049515851.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
STYK_RS00245 (STYK_00420)	-	46966..47838 (+)	873	WP_239822230.1	GHKL domain-containing protein	-
STYK_RS00250 (STYK_00430)	-	47835..48566 (+)	732	WP_049515847.1	response regulator transcription factor	-
STYK_RS00255 (STYK_00440)	-	49250..49447 (+)	198	WP_084923534.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
STYK_RS00265 (STYK_00460)	-	49661..49816 (+)	156	WP_000357248.1	smi_0061 family bacteriocin-like peptide	-
STYK_RS00270 (STYK_00470)	-	49820..50035 (+)	216	WP_080550793.1	bacteriocin immunity protein	-
STYK_RS00275 (STYK_00480)	-	50116..50295 (+)	180	WP_000846993.1	hypothetical protein	-
STYK_RS00280 (STYK_00490)	comA	50883..53036 (+)	2154	WP_261805017.1	peptide cleavage/export ABC transporter ComA	Regulator
STYK_RS00285 (STYK_00500)	comB	53049..54398 (+)	1350	WP_049551500.1	competence pheromone export protein ComB	Regulator
STYK_RS00290 (STYK_00510)	purC	54569..55276 (+)	708	WP_142358187.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
STYK_RS10240	-	55278..55421 (+)	144	WP_315972287.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80291.38 Da
• Isoelectric Point: 6.5175

>NTDB_id=85707 STYK_RS00280 WP_261805017.1 50883..53036(+) (comA) [Streptococcus toyakuensis strain TP1632]
MKFGKRHYRSQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKMLHYYVVIGQDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVNYLKKSFIYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDSKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGDMTFKQVSYKYGYGRDVLSDINLTIPQGSKVTFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILDNLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=85707 STYK_RS00280 WP_261805017.1 50883..53036(+) (comA) [Streptococcus toyakuensis strain TP1632]
ATGAAATTTGGGAAACGTCATTATCGTTCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGCTATTATTCTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGTTTTGAGACGCGAGCCATTAAGGCGGATATGACGCTTTTTGACTTGCCAGATTTG
ACCTTTCCTTTTGTTGCTCATGTGCTTAAGGAAGGAAAAATGCTCCACTACTATGTGGTAATTGGTCAGGATAAGGATAG
CATTCATATTGCCGATCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGCCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAACATCGTCCTAGCGACACTTTTGGTGACCCTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTTGGGATTATTTCTATTGGACTGGTCA
TCGTCTATATTCTCCAGCAGATCTTGTCTTACGCTCAGGAGTATCTCTTACTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTATCCTATATCAAACATGTTTTTCACCTGCCTATGTCCTTTTTTGCGACACGCAGGACAGGGGAAATCGTGTC
TCGTTTTACAGATGCTAACAGTATCATTGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCTCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACCTTATTGGCACTTCCTATCTATACAGTG
ATCATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAATGGTATTGAGACCATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAAATTGACAAGGAAT
TTGTGAATTATCTGAAGAAGTCCTTTATCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAAGTTGCCCATCTC
TTGCTCAATGTAGGCATTCTCTGGATGGGAGCTGTTCTGGTCATGGATAGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTGCAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTATATCTGGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTTGAGGATTTGAGCTTGATG
AAGGGAGATATGACCTTCAAGCAGGTTTCCTACAAGTATGGCTATGGTCGAGATGTCTTGTCAGATATCAATTTGACTAT
TCCGCAGGGTTCTAAGGTGACTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACATTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTATATC
AATTATCTGCCTCAGCAGCCCTATGTCTTTAACGGAACGATTTTGGACAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAAGAGGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGGGAGGATATCGAGCGTATGCCACTGAATTATCAGACAG
AGTTGACTTCGGATGGGGCAGGGATCTCAGGTGGTCAACGTCAGAGAATTGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACCAGCAGTTTGGATATTCTGACAGAGAAGCGGATTGTGGATAATCTGATGGCTTT
AGACAAGACCTTGATTTTCATTGCTCACCGTTTGACCATTGCTGAGCGGACAGAGAAAGTTGTTGTCTTGGATCAGGGCA
AGATTGTTGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGTGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	98.605	100	0.986
comA	Streptococcus mitis SK321	97.908	100	0.979
comA	Streptococcus pneumoniae Rx1	97.908	100	0.979
comA	Streptococcus pneumoniae D39	97.908	100	0.979
comA	Streptococcus pneumoniae R6	97.908	100	0.979
comA	Streptococcus pneumoniae TIGR4	97.49	100	0.975
comA	Streptococcus gordonii str. Challis substr. CH1	80.614	100	0.806
comA/nlmT	Streptococcus mutans UA159	65.132	100	0.651