Detailed information NTG0856144

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: QZH48_RS11535
• Genome accession: NZ_CP129879
• Coordinates: 2342100..2343173 (-)
• Length: 357 a.a.
• NCBI ID: WP_080739890.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain CAB701
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2337100..2348173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QZH48_RS11490 (QZH48_11490)	-	2337238..2338047 (-)	810	WP_038602349.1	metal ABC transporter permease	-
QZH48_RS11495 (QZH48_11495)	-	2338040..2338777 (-)	738	WP_021723055.1	metal ABC transporter ATP-binding protein	-
QZH48_RS11500 (QZH48_11500)	-	2338955..2339797 (-)	843	WP_038602352.1	metal ABC transporter substrate-binding protein	-
QZH48_RS11505 (QZH48_11505)	-	2339794..2340231 (-)	438	WP_021721874.1	zinc-dependent MarR family transcriptional regulator	-
QZH48_RS11510 (QZH48_11510)	comGG	2340312..2340587 (-)	276	WP_021721873.1	hypothetical protein	Machinery gene
QZH48_RS11515 (QZH48_11515)	comGF	2340635..2341060 (-)	426	WP_161935055.1	competence type IV pilus minor pilin ComGF	Machinery gene
QZH48_RS11520 (QZH48_11520)	comGE	2341044..2341340 (-)	297	WP_038602356.1	competence type IV pilus minor pilin ComGE	Machinery gene
QZH48_RS11525 (QZH48_11525)	comGD	2341312..2341710 (-)	399	WP_301675732.1	competence type IV pilus minor pilin ComGD	Machinery gene
QZH48_RS11530 (QZH48_11530)	comGC	2341703..2342086 (-)	384	WP_080739889.1	competence type IV pilus major pilin ComGC	Machinery gene
QZH48_RS11535 (QZH48_11535)	comGB	2342100..2343173 (-)	1074	WP_080739890.1	competence type IV pilus assembly protein ComGB	Machinery gene
QZH48_RS11540 (QZH48_11540)	comGA	2343067..2344005 (-)	939	WP_058205111.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 40374.52 Da
• Isoelectric Point: 10.3132

>NTDB_id=856144 QZH48_RS11535 WP_080739890.1 2342100..2343173(-) (comGB) [Lactococcus lactis subsp. lactis strain CAB701]
MSLGHQKIGIKKLISYLQMDISHLLKPRGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQSLSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLIHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
RLMQLIQPLVFVFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide

• Length: 1074 bp

>NTDB_id=856144 QZH48_RS11535 WP_080739890.1 2342100..2343173(-) (comGB) [Lactococcus lactis subsp. lactis strain CAB701]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACATCTACTGAAGCC
AAGAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTGAAAATGAAAGAAGGTCTCGCT
TCTGGTCAATCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGAACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTATTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTGCCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGATTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTCGAA
TTACGTCAAATTATTAACTTAATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCACTTTTTTTACCCGAGCTCTCATTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTGTTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCTATGTTACT
CCCCATCTATTCAAATATGGGTTCAGGAATATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (41-159)

• Type II secretion system (T2SS), protein F (T2SSF) (227-348)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	82.991	95.518	0.793
comYB	Streptococcus gordonii str. Challis substr. CH1	53.372	95.518	0.51
comYB	Streptococcus mutans UA159	53.079	95.518	0.507
comYB	Streptococcus mutans UA140	53.079	95.518	0.507
comGB/cglB	Streptococcus pneumoniae TIGR4	51.642	93.838	0.485
comGB/cglB	Streptococcus pneumoniae D39	51.642	93.838	0.485
comGB/cglB	Streptococcus pneumoniae R6	51.642	93.838	0.485
comGB/cglB	Streptococcus pneumoniae Rx1	51.642	93.838	0.485
comGB/cglB	Streptococcus mitis SK321	51.045	93.838	0.479
comGB/cglB	Streptococcus mitis NCTC 12261	50.149	93.838	0.471