Detailed information NTG0853964

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: QYM01_RS00285
• Genome accession: NZ_CP129527
• Coordinates: 47900..48814 (+)
• Length: 304 a.a.
• NCBI ID: WP_115251528.1
• Uniprot ID: A0A380KQA4
• Organism: Streptococcus equi subsp. zooepidemicus strain BJ-1
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42900..53814

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYM01_RS00265 (QYM01_00265)	purE	44057..44545 (+)	489	WP_301899820.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
QYM01_RS00270 (QYM01_00270)	purK	44532..45623 (+)	1092	WP_111677622.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
QYM01_RS00275 (QYM01_00275)	-	45633..45857 (+)	225	WP_111677623.1	phosphoribosylaminoimidazole carboxylase	-
QYM01_RS09935	-	45882..45953 (+)	72	Protein_34	hypothetical protein	-
QYM01_RS00280 (QYM01_00280)	purB	46311..47603 (+)	1293	WP_301899822.1	adenylosuccinate lyase	-
QYM01_RS00285 (QYM01_00285)	comR	47900..48814 (+)	915	WP_115251528.1	XRE family transcriptional regulator	Regulator
QYM01_RS09940	comS	48897..48995 (+)	99	WP_200831644.1	quorum-sensing system DWW-type pheromone	Regulator
QYM01_RS00290 (QYM01_00290)	ruvB	49029..50030 (+)	1002	WP_111677625.1	Holliday junction branch migration DNA helicase RuvB	-
QYM01_RS00295 (QYM01_00295)	-	50323..50781 (+)	459	WP_164336754.1	low molecular weight protein-tyrosine-phosphatase	-
QYM01_RS00300 (QYM01_00300)	-	50787..51188 (+)	402	WP_164336752.1	MORN repeat-containing protein	-
QYM01_RS00305 (QYM01_00305)	-	51185..52966 (+)	1782	WP_301899824.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35865.36 Da
• Isoelectric Point: 4.4139

>NTDB_id=853964 QYM01_RS00285 WP_115251528.1 47900..48814(+) (comR) [Streptococcus equi subsp. zooepidemicus strain BJ-1]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVIFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ

Nucleotide

• Length: 915 bp

>NTDB_id=853964 QYM01_RS00285 WP_115251528.1 47900..48814(+) (comR) [Streptococcus equi subsp. zooepidemicus strain BJ-1]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGATTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_19) (6-69)

• ComR tetratricopeptide (ComR_TPR) (73-296)

3D structure

• AlphaFold DB: A0A380KQA4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	75.248	99.671	0.75
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.069	95.395	0.497
comR	Streptococcus mutans UA159	48.495	98.355	0.477
comR	Streptococcus suis P1/7	38.591	98.026	0.378
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis D9	37.037	97.697	0.362