Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   V6U62_RS00795 Genome accession   NZ_CP145860
Coordinates   151416..152372 (+) Length   318 a.a.
NCBI ID   WP_227071975.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146416..157372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS00755 (V6U62_00750) - 147312..147674 (+) 363 WP_002887019.1 DUF1033 family protein -
  V6U62_RS00760 (V6U62_00755) comGA 147756..148697 (+) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U62_RS00765 (V6U62_00760) comGB 148579..149679 (+) 1101 WP_144429890.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U62_RS00770 (V6U62_00765) comGC 149676..150002 (+) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U62_RS00775 (V6U62_00770) comGD 149962..150390 (+) 429 WP_253183813.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U62_RS00780 (V6U62_00775) comGE 150422..150652 (+) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE Machinery gene
  V6U62_RS00785 (V6U62_00780) comGF 150639..151076 (+) 438 WP_227071977.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U62_RS00790 (V6U62_00785) comGG 151054..151371 (+) 318 WP_227071976.1 competence type IV pilus minor pilin ComGG Machinery gene
  V6U62_RS00795 (V6U62_00790) comGH 151416..152372 (+) 957 WP_227071975.1 class I SAM-dependent methyltransferase Machinery gene
  V6U62_RS00800 (V6U62_00795) - 152429..153622 (+) 1194 WP_410535066.1 acetate kinase -
  V6U62_RS00805 (V6U62_00800) - 153873..154070 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  V6U62_RS00810 (V6U62_00805) - 154082..154738 (+) 657 WP_410535064.1 CPBP family intramembrane glutamic endopeptidase -
  V6U62_RS00815 (V6U62_00810) - 154816..155262 (+) 447 WP_021144682.1 hypothetical protein -
  V6U62_RS00820 (V6U62_00815) - 155375..156037 (+) 663 WP_021144681.1 CPBP family intramembrane glutamic endopeptidase -
  V6U62_RS00825 (V6U62_00820) proC 156068..156838 (-) 771 WP_410535062.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35772.70 Da        Isoelectric Point: 4.4586

>NTDB_id=853129 V6U62_RS00795 WP_227071975.1 151416..152372(+) (comGH) [Streptococcus salivarius strain KSS2]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDVLEIGSGTGNLAETLLNNSQKNLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPKVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=853129 V6U62_RS00795 WP_227071975.1 151416..152372(+) (comGH) [Streptococcus salivarius strain KSS2]
ATGAATTTTGAAGCAATTGAGACAGCCTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCGCTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCCCTTAATCTAAGCAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAGCTAGGGCAATTG
GAAGCCTTACAAGCCAATCACCAGTTTACACCTGATGCTATTGGATTTATCATTCTTTACCTACTTGAAGGTTTGACCAA
GGACGACCAATTAGATGTTTTGGAGATTGGTTCGGGGACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
ACCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCAAGT
GCAGTTTATATCCAAGAAGATGCTGTTCGACCACATATTCTCAAAGAGAGTGATGTTATTATTAGTGACCTACCTGTTGG
TTACTACCCTAATGATGAAATTGCGAGTCGTTTCAAGGTTGCAGCAACTGGTGAACACACCTATGCTCATCACCTTCTCA
TGGAGCAATCACTCAAGTACTTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGTCCACAA
AGTGATTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCAGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTTAAAAAACAAACTGAAAATGCTCCTGAGACCTTTGTTTATCCACTTAGTG
ATTTGCAAAACCCAAAGGTCCTCAAAGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

70.159

99.057

0.695
  comGH Streptococcus mutans UA140

70.159

99.057

0.695