Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   QYR55_RS04530 Genome accession   NZ_CP129328
Coordinates   915595..916269 (+) Length   224 a.a.
NCBI ID   WP_003099507.1    Uniprot ID   -
Organism   Streptococcus iniae strain Si 1-19     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 910595..921269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYR55_RS04515 (QYR55_04515) pstB 911409..912167 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  QYR55_RS04520 (QYR55_04520) phoU 912222..912875 (+) 654 WP_367562025.1 phosphate signaling complex protein PhoU -
  QYR55_RS04525 (QYR55_04525) - 912937..915474 (+) 2538 WP_367562742.1 M1 family metallopeptidase -
  QYR55_RS04530 (QYR55_04530) ciaR 915595..916269 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  QYR55_RS04535 (QYR55_04535) ciaH 916262..917572 (+) 1311 WP_367562471.1 HAMP domain-containing sensor histidine kinase Regulator
  QYR55_RS04540 (QYR55_04540) rpsT 917744..917986 (-) 243 WP_220701811.1 30S ribosomal protein S20 -
  QYR55_RS04545 (QYR55_04545) coaA 918046..918967 (-) 922 Protein_832 type I pantothenate kinase -
  QYR55_RS04550 (QYR55_04550) - 919228..919827 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  QYR55_RS04555 (QYR55_04555) - 919814..921091 (+) 1278 WP_003099515.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25562.41 Da        Isoelectric Point: 4.3757

>NTDB_id=852258 QYR55_RS04530 WP_003099507.1 915595..916269(+) (ciaR) [Streptococcus iniae strain Si 1-19]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGFYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KESLDDKGHGFDLGADDYLTKPFYLEELKMRIQALLKRTGKMTTSQLSYGNISIDTERNMVKVGDTTIELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVDNLQTLRSVGYILKTNG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=852258 QYR55_RS04530 WP_003099507.1 915595..916269(+) (ciaR) [Streptococcus iniae strain Si 1-19]
ATGATAAAAATATTACTTGTTGAAGATGATTTAAGTTTATCTAATTCGATTTTTGATTTTTTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGAGATGAAGGTTTTTATGAGGCTGAAAGTGGTGTTTATGATCTTATTCTCCTGGACTTAATGT
TACCTGAAAAAAATGGTTTTCAAGTCCTAAAAGAATTAAGAGAAAAAGACATCAAAACGCCTGTTCTTATTATGACTGCT
AAAGAAAGTCTTGACGATAAAGGGCATGGCTTTGACCTTGGAGCTGATGACTACCTAACCAAACCATTTTATTTAGAGGA
GCTAAAAATGCGTATTCAAGCCCTCTTGAAACGAACTGGTAAGATGACTACCAGTCAGCTATCTTATGGGAATATCAGTA
TTGATACTGAACGAAATATGGTAAAAGTCGGAGACACTACCATTGAGCTTCTTGGAAAAGAGTATGATTTACTCATTTAT
CTCCTTCAAAATCAAAATGTTATTTTACCTAAATCACAGATTTTTGACCGTATATGGGGATTCGACAGTGATACCACAAT
ATCAGTTGTAGAGGTTTATGTTTCAAAAATCAGAAAAAAACTAAAAGGGACAGATTTTGTAGACAACCTTCAAACGCTTA
GAAGTGTCGGATACATCTTAAAAACAAATGGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371