Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   QYR57_RS04270 Genome accession   NZ_CP129327
Coordinates   873284..873958 (+) Length   224 a.a.
NCBI ID   WP_003099507.1    Uniprot ID   -
Organism   Streptococcus iniae strain Si 4-21     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 868284..878958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYR57_RS04255 (QYR57_04255) pstB 869098..869856 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  QYR57_RS04260 (QYR57_04260) phoU 869911..870564 (+) 654 WP_367562025.1 phosphate signaling complex protein PhoU -
  QYR57_RS04265 (QYR57_04265) - 870626..873163 (+) 2538 WP_367562026.1 M1 family metallopeptidase -
  QYR57_RS04270 (QYR57_04270) ciaR 873284..873958 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  QYR57_RS04275 (QYR57_04275) ciaH 873951..875261 (+) 1311 WP_003099509.1 cell wall metabolism sensor histidine kinase WalK Regulator
  QYR57_RS04280 (QYR57_04280) rpsT 875433..875675 (-) 243 WP_220701811.1 30S ribosomal protein S20 -
  QYR57_RS04285 (QYR57_04285) coaA 875735..876657 (-) 923 Protein_814 type I pantothenate kinase -
  QYR57_RS04290 (QYR57_04290) - 876918..877517 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  QYR57_RS04295 (QYR57_04295) - 877504..878781 (+) 1278 WP_367562027.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25562.41 Da        Isoelectric Point: 4.3757

>NTDB_id=852212 QYR57_RS04270 WP_003099507.1 873284..873958(+) (ciaR) [Streptococcus iniae strain Si 4-21]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGFYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KESLDDKGHGFDLGADDYLTKPFYLEELKMRIQALLKRTGKMTTSQLSYGNISIDTERNMVKVGDTTIELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVDNLQTLRSVGYILKTNG

Nucleotide


Download         Length: 675 bp        

>NTDB_id=852212 QYR57_RS04270 WP_003099507.1 873284..873958(+) (ciaR) [Streptococcus iniae strain Si 4-21]
ATGATAAAAATATTACTTGTTGAAGATGATTTAAGTTTATCTAATTCGATTTTTGATTTTTTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGAGATGAAGGTTTTTATGAGGCTGAAAGTGGTGTTTATGATCTTATTCTCCTGGACTTAATGT
TACCTGAAAAAAATGGTTTTCAAGTCCTAAAAGAATTAAGAGAAAAAGACATCAAAACGCCTGTTCTTATTATGACTGCT
AAAGAAAGTCTTGACGATAAAGGGCATGGCTTTGACCTTGGAGCTGATGACTACCTAACCAAACCATTTTATTTAGAGGA
GCTAAAAATGCGTATTCAAGCCCTCTTGAAACGAACTGGTAAGATGACTACCAGTCAGCTATCTTATGGGAATATCAGTA
TTGATACTGAACGAAATATGGTAAAAGTCGGAGACACTACCATTGAGCTTCTTGGAAAAGAGTATGATTTACTCATTTAT
CTCCTTCAAAATCAAAATGTTATTTTACCTAAATCACAGATTTTTGACCGTATATGGGGATTCGACAGTGATACCACAAT
ATCAGTTGTAGAGGTTTATGTTTCAAAAATCAGAAAAAAACTAAAAGGGACAGATTTTGTAGACAACCTTCAAACGCTTA
GAAGTGTCGGATACATCTTAAAAACAAATGGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371