Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   QYR57_RS04275 Genome accession   NZ_CP129327
Coordinates   873951..875261 (+) Length   436 a.a.
NCBI ID   WP_003099509.1    Uniprot ID   A0A3L8GJR1
Organism   Streptococcus iniae strain Si 4-21     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 868951..880261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYR57_RS04255 (QYR57_04255) pstB 869098..869856 (+) 759 WP_003099501.1 phosphate ABC transporter ATP-binding protein PstB -
  QYR57_RS04260 (QYR57_04260) phoU 869911..870564 (+) 654 WP_367562025.1 phosphate signaling complex protein PhoU -
  QYR57_RS04265 (QYR57_04265) - 870626..873163 (+) 2538 WP_367562026.1 M1 family metallopeptidase -
  QYR57_RS04270 (QYR57_04270) ciaR 873284..873958 (+) 675 WP_003099507.1 response regulator transcription factor Regulator
  QYR57_RS04275 (QYR57_04275) ciaH 873951..875261 (+) 1311 WP_003099509.1 cell wall metabolism sensor histidine kinase WalK Regulator
  QYR57_RS04280 (QYR57_04280) rpsT 875433..875675 (-) 243 WP_220701811.1 30S ribosomal protein S20 -
  QYR57_RS04285 (QYR57_04285) coaA 875735..876657 (-) 923 Protein_814 type I pantothenate kinase -
  QYR57_RS04290 (QYR57_04290) - 876918..877517 (+) 600 WP_003099513.1 class I SAM-dependent methyltransferase -
  QYR57_RS04295 (QYR57_04295) - 877504..878781 (+) 1278 WP_367562027.1 pyrimidine-nucleoside phosphorylase -
  QYR57_RS04300 (QYR57_04300) deoC 878793..879455 (+) 663 WP_003099517.1 deoxyribose-phosphate aldolase -
  QYR57_RS04305 (QYR57_04305) - 879427..879831 (+) 405 WP_230453495.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49969.52 Da        Isoelectric Point: 9.1099

>NTDB_id=852213 QYR57_RS04275 WP_003099509.1 873951..875261(+) (ciaH) [Streptococcus iniae strain Si 4-21]
MANLKRIYQSDNFGHFFHFFAVFTGIFVVMTMIIIQIMQYGVYSSVDSSLLAVSKNSSVYANLTMERMTSFYFDNQEDAF
KNGTEVFKAALVEQPVANTDIILFSSNGTVLNSFDALSGFQNFTLKTNELNAIRTRKLMNFYGHEEKYHTLTVKIHSNRY
PAVAYLMAVVNVEQLDRANERYERIIVLVMITFWFISVLASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNETILENSEPIASSLEEVRNMKILTTNLLNLARRDDGINPELVDVDASFFDAMFENFNLVAEDYGKDFHFEN
QVKRTIKMDKSLLKQLITILFDNALKYTDSDGQISISVRTTDKNLMVRVLDDGPGIKDMDKKKVFDRFYRVDKARTRTKG
GFGLGLSLAKQIVASLNGTISVKDNKPKGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=852213 QYR57_RS04275 WP_003099509.1 873951..875261(+) (ciaH) [Streptococcus iniae strain Si 4-21]
ATGGCTAATTTAAAACGTATTTACCAGTCAGATAATTTTGGGCATTTTTTCCATTTTTTTGCAGTCTTTACAGGAATATT
TGTTGTCATGACCATGATTATCATTCAAATCATGCAGTACGGTGTTTATTCTTCGGTAGATAGTAGTCTACTTGCTGTGT
CAAAAAATTCATCGGTTTATGCTAATTTAACCATGGAACGAATGACCTCATTTTACTTTGATAATCAAGAGGATGCTTTT
AAAAATGGAACTGAAGTCTTTAAAGCGGCCTTAGTTGAACAACCAGTTGCCAATACGGATATTATCCTCTTTAGTTCTAA
CGGAACGGTTTTAAATAGCTTTGATGCGCTATCGGGTTTTCAAAATTTTACCTTAAAAACAAATGAATTAAATGCCATTC
GAACACGGAAATTGATGAATTTTTACGGGCATGAAGAAAAATACCATACGCTGACAGTTAAGATTCATTCCAATAGGTAC
CCAGCGGTGGCTTACCTAATGGCAGTTGTCAATGTGGAACAATTGGACCGTGCCAATGAGCGCTATGAACGAATCATTGT
TCTTGTTATGATAACTTTCTGGTTTATTTCTGTTTTGGCCAGTATATACCTTGCAAAATGGAGTCGTAAACCAATTCTTG
AAAGTTATGAGAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGAACTCCCTTAGCAGTATTACAAAATCGC
TTAGAGACCCTGTTTAGAAAACCTAATGAAACAATTCTGGAAAACAGTGAACCAATTGCTTCGAGTTTAGAAGAAGTGCG
CAATATGAAGATCTTAACCACAAATTTATTGAATCTTGCCAGACGCGATGATGGGATTAATCCAGAACTCGTTGATGTGG
ATGCAAGCTTTTTTGACGCTATGTTTGAAAACTTCAACTTAGTAGCTGAAGATTATGGTAAAGACTTCCATTTTGAAAAT
CAGGTTAAGCGGACAATAAAAATGGATAAATCTTTATTAAAACAATTGATTACCATTTTATTTGATAATGCTTTGAAATA
CACGGACTCTGATGGGCAAATTTCAATTAGTGTTCGAACAACAGATAAAAATTTAATGGTCAGAGTGCTAGATGATGGTC
CTGGAATAAAAGACATGGATAAAAAGAAAGTTTTTGACCGCTTCTATCGTGTTGATAAGGCTAGAACACGTACTAAAGGT
GGATTTGGTTTGGGACTTTCTTTAGCAAAACAGATTGTTGCTTCCTTAAATGGAACAATATCAGTTAAAGACAATAAACC
AAAAGGGACAATATTTGAAGTTAAACTCTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GJR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.275

99.312

0.569
  ciaH Streptococcus pneumoniae Rx1

51.835

100

0.518
  ciaH Streptococcus pneumoniae D39

51.835

100

0.518
  ciaH Streptococcus pneumoniae R6

51.835

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.835

100

0.518