Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   QWH96_RS05950 Genome accession   NZ_CP128987
Coordinates   1162910..1163584 (-) Length   224 a.a.
NCBI ID   WP_003060678.1    Uniprot ID   A0AAE9R380
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NS3396     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1157910..1168584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWH96_RS05925 (QWH96_05925) - 1158095..1159372 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  QWH96_RS05930 (QWH96_05930) - 1159359..1159958 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  QWH96_RS05935 (QWH96_05935) coaA 1160227..1161147 (+) 921 WP_003058858.1 type I pantothenate kinase -
  QWH96_RS05940 (QWH96_05940) rpsT 1161201..1161449 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  QWH96_RS05945 (QWH96_05945) ciaH 1161607..1162917 (-) 1311 WP_049520023.1 HAMP domain-containing sensor histidine kinase Regulator
  QWH96_RS05950 (QWH96_05950) ciaR 1162910..1163584 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  QWH96_RS05955 (QWH96_05955) - 1163788..1166325 (-) 2538 WP_049520024.1 M1 family metallopeptidase -
  QWH96_RS05960 (QWH96_05960) phoU 1166526..1167179 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  QWH96_RS05965 (QWH96_05965) pstB 1167257..1168015 (-) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25601.58 Da        Isoelectric Point: 4.4684

>NTDB_id=850188 QWH96_RS05950 WP_003060678.1 1162910..1163584(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=850188 QWH96_RS05950 WP_003060678.1 1162910..1163584(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGCTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375