Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   QWH96_RS05945 Genome accession   NZ_CP128987
Coordinates   1161607..1162917 (-) Length   436 a.a.
NCBI ID   WP_049520023.1    Uniprot ID   A0AAE9QT75
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NS3396     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1156607..1167917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QWH96_RS05915 (QWH96_05915) - 1157041..1157430 (-) 390 WP_049520019.1 cytidine deaminase -
  QWH96_RS05920 (QWH96_05920) deoC 1157417..1158079 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  QWH96_RS05925 (QWH96_05925) - 1158095..1159372 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  QWH96_RS05930 (QWH96_05930) - 1159359..1159958 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  QWH96_RS05935 (QWH96_05935) coaA 1160227..1161147 (+) 921 WP_003058858.1 type I pantothenate kinase -
  QWH96_RS05940 (QWH96_05940) rpsT 1161201..1161449 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  QWH96_RS05945 (QWH96_05945) ciaH 1161607..1162917 (-) 1311 WP_049520023.1 HAMP domain-containing sensor histidine kinase Regulator
  QWH96_RS05950 (QWH96_05950) ciaR 1162910..1163584 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  QWH96_RS05955 (QWH96_05955) - 1163788..1166325 (-) 2538 WP_049520024.1 M1 family metallopeptidase -
  QWH96_RS05960 (QWH96_05960) phoU 1166526..1167179 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49988.50 Da        Isoelectric Point: 8.8346

>NTDB_id=850187 QWH96_RS05945 WP_049520023.1 1161607..1162917(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MNKLKKEVFSDQYNHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSRINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDRALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=850187 QWH96_RS05945 WP_049520023.1 1161607..1162917(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACAACCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCGGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGAAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAGGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.37

100

0.516
  ciaH Streptococcus pneumoniae D39

51.37

100

0.516
  ciaH Streptococcus pneumoniae R6

51.37

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.37

100

0.516