Detailed information NTG0850152

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: QWH96_RS00295
• Genome accession: NZ_CP128987
• Coordinates: 50876..51787 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NS3396
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45876..56787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QWH96_RS00270 (QWH96_00270)	purE	46376..46864 (+)	489	WP_066028650.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
QWH96_RS00275 (QWH96_00275)	purK	46851..47924 (+)	1074	WP_338433680.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
QWH96_RS00280 (QWH96_00280)	-	47934..49190 (+)	1257	WP_003055555.1	DUF4041 domain-containing protein	-
QWH96_RS00285 (QWH96_00285)	-	49183..49392 (+)	210	WP_014611912.1	hypothetical protein	-
QWH96_RS00290 (QWH96_00290)	purB	49441..50733 (+)	1293	WP_049519794.1	adenylosuccinate lyase	-
QWH96_RS00295 (QWH96_00295)	comR	50876..51787 (+)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
QWH96_RS00300 (QWH96_00300)	comS	51874..51972 (+)	99	WP_198763767.1	quorum-sensing system DWW-type pheromone	Regulator
QWH96_RS00305 (QWH96_00305)	ruvB	52006..53004 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	-
QWH96_RS00310 (QWH96_00310)	-	53139..53570 (+)	432	WP_048327929.1	low molecular weight protein-tyrosine-phosphatase	-
QWH96_RS00315 (QWH96_00315)	-	53599..54000 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
QWH96_RS00320 (QWH96_00320)	-	53997..55772 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=850152 QWH96_RS00295 WP_003060893.1 50876..51787(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=850152 QWH96_RS00295 WP_003060893.1 50876..51787(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTTATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCTGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363