Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   L6410_RS00370 Genome accession   NZ_AP024276
Coordinates   64949..66301 (+) Length   450 a.a.
NCBI ID   WP_024397560.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SUT-286     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 59949..71301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6410_RS00355 (SUT286_00530) - 61813..61965 (+) 153 WP_079269043.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6410_RS11005 (SUT286_00540) - 62027..62155 (+) 129 WP_261311026.1 hypothetical protein -
  L6410_RS00360 (SUT286_00550) - 62152..62313 (+) 162 WP_237395554.1 hypothetical protein -
  L6410_RS00365 (SUT286_00560) comA 62784..64937 (+) 2154 WP_237395556.1 peptide cleavage/export ABC transporter ComA Regulator
  L6410_RS00370 (SUT286_00570) comB 64949..66301 (+) 1353 WP_024397560.1 bacteriocin secretion accessory protein Regulator
  L6410_RS00375 (SUT286_00580) - 66690..66869 (+) 180 WP_237395558.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6410_RS00380 (SUT286_00590) - 66870..67070 (+) 201 WP_237395559.1 hypothetical protein -
  L6410_RS00385 (SUT286_00600) - 67087..67278 (+) 192 WP_024392851.1 hypothetical protein -
  L6410_RS00390 (SUT286_00610) - 67963..68832 (-) 870 WP_205028832.1 cysteine ABC transporter substrate-binding protein -
  L6410_RS00395 (SUT286_00620) - 68845..69591 (-) 747 WP_237395561.1 amino acid ABC transporter ATP-binding protein -
  L6410_RS00400 (SUT286_00630) - 69596..70273 (-) 678 WP_024392848.1 amino acid ABC transporter permease -
  L6410_RS00405 (SUT286_00640) - 70254..70913 (-) 660 WP_237396593.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50724.18 Da        Isoelectric Point: 4.6857

>NTDB_id=84453 L6410_RS00370 WP_024397560.1 64949..66301(+) (comB) [Streptococcus parasuis strain SUT-286]
MDHHLLESAEFYNRRYHNAASRVIIPSCVLFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSTSNHQILRNHLIENQE
ISVGDLLVEYQSENEQIQEDKVKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCNQLETLASTIDQQN
ATIASQNQAAKQSQLELEKVMHQTEKALADYRELKWAIQSDGVIDEENVGYSIYAQYQLAQSEDAVASQESFVAQIDNQI
SQVETQLASYKLQYAGAGVQQSYTNSLDSQSASLEAQYLTKVGQEMTLLSSQLRELEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLTEAKKMKITAYIPSKDIASISLKDNIQFSLQGKGEKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=84453 L6410_RS00370 WP_024397560.1 64949..66301(+) (comB) [Streptococcus parasuis strain SUT-286]
ATGGACCATCATCTGTTAGAAAGTGCGGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTGTATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCTAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCTGTACAACGATTGGCACAGATTCACTCAACCAGTAATCATCAGATTCTGAGGAATCATTTAATCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTAGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGGTCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAGAGTTTGGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCAATCAATTAGAAACATTGGCAAGTACGATTGATCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCCGCAAAACAATCACAATTGGAATTGGAAAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATGGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGTTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCGTCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCTGGTGCAGGAGTACAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCATTGGAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGAACTAGAAGCAACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAAGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCCGTTCTAACGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CATTACAAGGGAAGGGAGAGAAACGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGGATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAGTTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

49.889

99.778

0.498
  comB Streptococcus pneumoniae D39

47.778

100

0.478
  comB Streptococcus pneumoniae R6

47.778

100

0.478
  comB Streptococcus pneumoniae Rx1

47.778

100

0.478
  comB Streptococcus pneumoniae TIGR4

47.333

100

0.473
  comB Streptococcus mitis NCTC 12261

46.444

100

0.464
  comB Streptococcus mitis SK321

46.222

100

0.462

Multiple sequence alignment