Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   L6410_RS00365 Genome accession   NZ_AP024276
Coordinates   62784..64937 (+) Length   717 a.a.
NCBI ID   WP_237395556.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SUT-286     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 57784..69937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6410_RS00350 (SUT286_00510) - 59459..60727 (+) 1269 WP_237395552.1 MerR family transcriptional regulator -
  L6410_RS00355 (SUT286_00530) - 61813..61965 (+) 153 WP_079269043.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6410_RS11005 (SUT286_00540) - 62027..62155 (+) 129 WP_261311026.1 hypothetical protein -
  L6410_RS00360 (SUT286_00550) - 62152..62313 (+) 162 WP_237395554.1 hypothetical protein -
  L6410_RS00365 (SUT286_00560) comA 62784..64937 (+) 2154 WP_237395556.1 peptide cleavage/export ABC transporter ComA Regulator
  L6410_RS00370 (SUT286_00570) comB 64949..66301 (+) 1353 WP_024397560.1 bacteriocin secretion accessory protein Regulator
  L6410_RS00375 (SUT286_00580) - 66690..66869 (+) 180 WP_237395558.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6410_RS00380 (SUT286_00590) - 66870..67070 (+) 201 WP_237395559.1 hypothetical protein -
  L6410_RS00385 (SUT286_00600) - 67087..67278 (+) 192 WP_024392851.1 hypothetical protein -
  L6410_RS00390 (SUT286_00610) - 67963..68832 (-) 870 WP_205028832.1 cysteine ABC transporter substrate-binding protein -
  L6410_RS00395 (SUT286_00620) - 68845..69591 (-) 747 WP_237395561.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81122.37 Da        Isoelectric Point: 7.0405

>NTDB_id=84452 L6410_RS00365 WP_237395556.1 62784..64937(+) (comA) [Streptococcus parasuis strain SUT-286]
MKFGKRHYRAQVDTRDCGVAALAMILEYYRSHHSLASLREMAKTTMEGTTAFGLVKVAEELGFETRAIKADMSLFSMREA
VYPFIAHVVKDGTLLHYYVVIGADKKYIYIADPDPSVKLTKLSHEQFEKEWTGVSLFMAPKPEYQPHKEKSHGLLSFIPL
LTKQKGLITNIVLATLLVTFINIVGSYYLQSIIDTYVPNQMKTTLGVISVGLVVVYALQQLLSYSQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVVVVSVVLFSQNVYLFFISLLALPIYTL
IIFAFMKPFEKMNQEVMESNAILSSSIIEDINGIETIKSLTSEKQRYQKIDREFVDYLQKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGACLVMDQKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTAQVANTRLNEVYLVESEFAEKKSVTDLSLL
SGDIECNKVHYKYGYGRDVLTDINLKIKRGEKVSFVGVSGSGKTTLAKMMVDFYDPYKGEIRLNNVNINQIDKQTLRQHI
NYLPQQPYVFNGTILENLLLGAKEGTSQEDILWAVEMACIREDIEKMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLSLDKTLIFIAHRLTIAERTEHIVVLDKGRIVEQGSHKELLDKQGFYEYLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=84452 L6410_RS00365 WP_237395556.1 62784..64937(+) (comA) [Streptococcus parasuis strain SUT-286]
ATGAAATTTGGAAAACGTCATTATAGAGCACAAGTAGATACACGAGACTGTGGTGTAGCAGCGCTTGCTATGATCTTGGA
ATATTATCGTTCTCATCATTCTTTAGCAAGTTTGCGAGAAATGGCAAAGACAACTATGGAAGGCACGACAGCATTTGGTT
TAGTAAAGGTTGCTGAAGAGCTAGGGTTTGAGACGCGTGCGATTAAGGCAGATATGTCTTTGTTTTCGATGAGGGAAGCG
GTCTATCCTTTCATTGCCCATGTGGTAAAAGATGGCACGTTACTACATTATTATGTTGTCATTGGGGCAGATAAGAAATA
TATCTATATTGCAGACCCGGATCCATCAGTGAAATTAACAAAGTTATCCCATGAACAATTTGAAAAGGAGTGGACAGGAG
TTTCGCTATTCATGGCTCCCAAACCGGAATATCAACCTCATAAAGAGAAGAGTCATGGGTTACTTTCTTTCATTCCATTG
TTGACTAAACAAAAGGGATTGATTACAAATATTGTTCTCGCAACGCTCTTGGTTACTTTCATCAACATTGTGGGCTCCTA
TTATTTACAATCCATTATTGACACTTATGTTCCAAATCAGATGAAAACAACATTAGGTGTCATTTCAGTCGGTTTGGTGG
TTGTTTATGCCCTGCAACAATTGTTATCTTATTCCCAAGAGTATTTATTAATCATTCTTGGGCAACGACTCTCTATTGAT
GTGATTTTGTCTTATATTAGACATGTTTTTCATCTACCAATGTCATTTTTTGCTACTCGGCGAACTGGGGAAATTGTTTC
ACGATTTACAGATGCCAATTCTATTATTGATGCTTTAGCTAGTACCATTCTATCAATATTTTTGGATGTATCTATTGTTG
TGGTTGTTTCGGTAGTGCTGTTTAGTCAGAATGTCTATCTTTTCTTTATTTCCTTGTTGGCATTGCCAATCTATACTCTA
ATCATTTTTGCGTTTATGAAACCATTTGAAAAGATGAATCAAGAAGTGATGGAAAGTAATGCAATTCTTTCTTCGTCTAT
CATTGAAGATATCAATGGTATTGAAACCATAAAATCATTGACAAGTGAGAAACAACGTTATCAGAAAATTGATAGAGAAT
TTGTAGATTATTTACAAAAATCATTTGCATACAACAAGGCCGAAGGGCAGCAAAAAGTGTTAAAGCGCTTGGCCCAACTC
GTATTAAATGTAGCTATTCTTTGGTTAGGAGCTTGTCTTGTTATGGATCAGAAAATGACTTTGGGGCAGCTAATCACCTT
CAATACCTTATTGGTCTATTTCACGAATCCATTGGAAAATATAATCAATTTACAAACAAAATTACAGACAGCTCAAGTTG
CCAATACCCGCTTGAACGAGGTCTATTTGGTTGAATCGGAATTTGCTGAAAAGAAATCCGTGACGGACCTTTCGTTACTT
TCGGGGGATATTGAATGCAACAAAGTGCATTATAAATATGGCTATGGTAGGGATGTTTTGACAGATATTAATTTGAAAAT
TAAACGAGGGGAAAAGGTCTCCTTTGTTGGAGTTTCTGGTTCTGGGAAGACGACGTTGGCTAAAATGATGGTGGATTTTT
ATGATCCTTACAAGGGTGAGATTCGATTAAATAATGTCAACATTAATCAAATCGATAAGCAAACACTTCGTCAGCATATC
AATTATCTTCCACAGCAACCCTATGTTTTTAATGGGACAATTCTCGAAAATCTATTGCTAGGTGCAAAAGAGGGAACAAG
TCAAGAAGATATTTTGTGGGCTGTTGAAATGGCATGTATTAGAGAAGATATTGAAAAAATGCCACTGAATTACCAAACGG
AATTGACTTCTGATGGAGCCGGAATTTCCGGTGGACAACGGCAGCGAATTGCCTTGGCGCGTGCCCTTCTTACGGATGCC
CCTATTATGATTTTGGATGAGGCAACCAGTAGTCTGGATATTTTGACAGAGAAGCGTATTGTGGACAACCTATTGTCATT
GGACAAAACACTGATTTTTATTGCTCATCGTTTAACCATTGCAGAGCGTACTGAACATATTGTTGTGCTAGATAAGGGAA
GAATTGTAGAACAAGGGAGTCATAAGGAATTGTTAGACAAGCAAGGGTTCTATGAATATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

79.637

100

0.796
  comA Streptococcus pneumoniae D39

79.637

100

0.796
  comA Streptococcus pneumoniae R6

79.637

100

0.796
  comA Streptococcus mitis NCTC 12261

79.498

100

0.795
  comA Streptococcus pneumoniae TIGR4

79.358

100

0.794
  comA Streptococcus mitis SK321

79.358

100

0.794
  comA Streptococcus gordonii str. Challis substr. CH1

77.266

100

0.773
  comA/nlmT Streptococcus mutans UA159

63.459

100

0.635

Multiple sequence alignment