Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QUD66_RS10460 Genome accession   NZ_AP027156
Coordinates   2139763..2140419 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain JNE181771     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2134763..2145419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUD66_RS10430 (JNE181771_19890) yecA 2136014..2136679 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  QUD66_RS10450 (JNE181771_19900) pgsA 2137329..2137877 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QUD66_RS10455 (JNE181771_19910) uvrC 2137934..2139766 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QUD66_RS10460 (JNE181771_19920) letA 2139763..2140419 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QUD66_RS25110 - 2140561..2140632 (+) 72 Protein_2056 transcriptional regulator -
  QUD66_RS10465 yecU 2140715..2140891 (+) 177 WP_000590347.1 protein YecU -
  QUD66_RS10470 (JNE181771_19930) yecF 2140878..2141102 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QUD66_RS10475 (JNE181771_19940) sdiA 2141169..2141891 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  QUD66_RS10480 (JNE181771_19950) tcyN 2142121..2142873 (-) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QUD66_RS10485 (JNE181771_19960) tcyL 2142870..2143538 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QUD66_RS10490 (JNE181771_19970) dcyD 2143553..2144539 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=83944 QUD66_RS10460 WP_000611335.1 2139763..2140419(-) (letA) [Escherichia coli strain JNE181771]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=83944 QUD66_RS10460 WP_000611335.1 2139763..2140419(-) (letA) [Escherichia coli strain JNE181771]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment