Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   VOI49_RS00370 Genome accession   NZ_CP142018
Coordinates   57197..58108 (+) Length   303 a.a.
NCBI ID   WP_115246948.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain lu24     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52197..63108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS00350 purD 52676..53938 (+) 1263 WP_003049071.1 phosphoribosylamine--glycine ligase -
  VOI49_RS00355 purE 54193..54681 (+) 489 WP_003049074.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  VOI49_RS00360 purK 54668..55753 (+) 1086 WP_003049077.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  VOI49_RS00365 purB 55763..57055 (+) 1293 WP_003049079.1 adenylosuccinate lyase -
  VOI49_RS00370 comR 57197..58108 (+) 912 WP_115246948.1 helix-turn-helix domain-containing protein Regulator
  VOI49_RS00375 - 58165..59340 (-) 1176 WP_243093136.1 IS256 family transposase -
  VOI49_RS00380 comS 59518..59616 (+) 99 WP_014611913.1 quorum-sensing system DWW-type pheromone Regulator
  VOI49_RS00385 ruvB 59650..60648 (+) 999 WP_226314012.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  VOI49_RS00390 - 60783..61214 (+) 432 WP_003049087.1 low molecular weight protein-tyrosine-phosphatase -
  VOI49_RS00395 - 61243..61644 (+) 402 WP_003049089.1 MORN repeat-containing protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35952.51 Da        Isoelectric Point: 4.6780

>NTDB_id=839140 VOI49_RS00370 WP_115246948.1 57197..58108(+) (comR) [Streptococcus dysgalactiae strain lu24]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEERIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKRTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide


Download         Length: 912 bp        

>NTDB_id=839140 VOI49_RS00370 WP_115246948.1 57197..58108(+) (comR) [Streptococcus dysgalactiae strain lu24]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTATGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCAAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGGAAATTGCAAGTCCGAGAGTCTCAGTTTGATGAGATATTCGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAGAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAGAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTCACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTGTTAGAAGATTTATTTCTATTAAATAATATTCTTTTGT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAACGAATGCCCATGTATTGCATGTATGAATGGAAATTATCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCATCTTAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

83.056

99.34

0.825
  comR Streptococcus pyogenes MGAS8232

55.298

99.67

0.551
  comR Streptococcus mutans UA159

45.819

98.68

0.452
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

46.575

96.37

0.449