Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   VF946_RS07070 Genome accession   NZ_CP141824
Coordinates   1367992..1368663 (-) Length   223 a.a.
NCBI ID   WP_024394126.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1362992..1373663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS07050 coaA 1363578..1364498 (+) 921 WP_002935283.1 type I pantothenate kinase -
  VF946_RS07055 rpsT 1364557..1364805 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  VF946_RS07060 - 1365067..1366296 (-) 1230 WP_023369936.1 transglutaminase domain-containing protein -
  VF946_RS07065 ciaH 1366620..1367999 (-) 1380 WP_024383407.1 sensor histidine kinase Regulator
  VF946_RS07070 ciaR 1367992..1368663 (-) 672 WP_024394126.1 response regulator transcription factor Regulator
  VF946_RS07075 - 1368857..1369237 (-) 381 WP_023369940.1 hypothetical protein -
  VF946_RS07080 - 1369622..1370824 (+) 1203 WP_074389402.1 IS110 family transposase -
  VF946_RS07085 phoU 1371026..1371682 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  VF946_RS07090 pstB 1371711..1372469 (-) 759 WP_329894429.1 phosphate ABC transporter ATP-binding protein PstB -
  VF946_RS07095 pstB 1372481..1373284 (-) 804 WP_074389641.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25306.00 Da        Isoelectric Point: 4.2183

>NTDB_id=838191 VF946_RS07070 WP_024394126.1 1367992..1368663(-) (ciaR) [Streptococcus suis strain HB18]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=838191 VF946_RS07070 WP_024394126.1 1367992..1368663(-) (ciaR) [Streptococcus suis strain HB18]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGATCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGACCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.583

100

0.906
  ciaR Streptococcus pneumoniae Rx1

88.789

100

0.888
  ciaR Streptococcus pneumoniae D39

88.789

100

0.888
  ciaR Streptococcus pneumoniae R6

88.789

100

0.888
  ciaR Streptococcus pneumoniae TIGR4

88.789

100

0.888
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.053

100

0.386
  vicR Streptococcus mutans UA159

35.897

100

0.377
  micA Streptococcus pneumoniae Cp1015

34.764

100

0.363