Detailed information
Bioinformatically predicted
Overview
| Name | pilC | Type | Machinery gene |
| Locus tag | Hhaem_RS00615 | Genome accession | NZ_AP024093 |
| Coordinates | 124775..125995 (+) | Length | 406 a.a. |
| NCBI ID | WP_223893699.1 | Uniprot ID | - |
| Organism | Haemophilus haemolyticus strain 2019-19 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 119775..130995
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Hhaem_RS00590 (Hhaem_01200) | - | 120365..121162 (-) | 798 | WP_223893694.1 | sulfite exporter TauE/SafE family protein | - |
| Hhaem_RS00595 (Hhaem_01210) | rppH | 121162..121752 (-) | 591 | WP_118813215.1 | RNA pyrophosphohydrolase | - |
| Hhaem_RS00600 (Hhaem_01220) | ampD | 122278..122832 (-) | 555 | WP_223893695.1 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | - |
| Hhaem_RS00605 (Hhaem_01230) | pilA | 122947..123387 (+) | 441 | WP_223893697.1 | prepilin peptidase-dependent pilin | Machinery gene |
| Hhaem_RS00610 (Hhaem_01240) | pilB | 123384..124778 (+) | 1395 | WP_223893698.1 | GspE/PulE family protein | Machinery gene |
| Hhaem_RS00615 (Hhaem_01250) | pilC | 124775..125995 (+) | 1221 | WP_223893699.1 | type II secretion system F family protein | Machinery gene |
| Hhaem_RS00620 (Hhaem_01260) | pilD | 125992..126684 (+) | 693 | WP_223893700.1 | A24 family peptidase | Machinery gene |
| Hhaem_RS00625 (Hhaem_01270) | rho | 126738..128000 (-) | 1263 | WP_005629550.1 | transcription termination factor Rho | - |
| Hhaem_RS00630 (Hhaem_01280) | metJ | 128248..128565 (+) | 318 | WP_005634287.1 | met regulon transcriptional regulator MetJ | - |
| Hhaem_RS00635 (Hhaem_01290) | cueR | 128579..128965 (-) | 387 | WP_005629546.1 | Cu(I)-responsive transcriptional regulator | - |
| Hhaem_RS00640 (Hhaem_01300) | - | 129042..129248 (+) | 207 | WP_223893701.1 | heavy-metal-associated domain-containing protein | - |
Sequence
Protein
Download Length: 406 a.a. Molecular weight: 46394.59 Da Isoelectric Point: 9.8218
>NTDB_id=83416 Hhaem_RS00615 WP_223893699.1 124775..125995(+) (pilC) [Haemophilus haemolyticus strain 2019-19]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSRSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSDNNAELPTITAILLFISNFLKQNIGILLFFAFSFFLFYYFYLKRQAWF
HQQKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSELFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSRSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSDNNAELPTITAILLFISNFLKQNIGILLFFAFSFFLFYYFYLKRQAWF
HQQKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSELFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ
Nucleotide
Download Length: 1221 bp
>NTDB_id=83416 Hhaem_RS00615 WP_223893699.1 124775..125995(+) (pilC) [Haemophilus haemolyticus strain 2019-19]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCAACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGCAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCGATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTGTACCCATCAATGGTGTTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATTGTGCCTCAATT
TGCTGAAATGTATAGTGACAATAATGCTGAATTACCAACAATAACCGCAATATTGCTCTTTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGGCCTGGTTT
CATCAACAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAAGCACTAGATAGTTTTCTCCCTCGCACACAAACTT
GGCAAACCAAGAAAACCCTCGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGAGCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCGGTTATTCAATGA
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCAACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGCAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCGATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTGTACCCATCAATGGTGTTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATTGTGCCTCAATT
TGCTGAAATGTATAGTGACAATAATGCTGAATTACCAACAATAACCGCAATATTGCTCTTTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGGCCTGGTTT
CATCAACAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAAGCACTAGATAGTTTTCTCCCTCGCACACAAACTT
GGCAAACCAAGAAAACCCTCGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGAGCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCGGTTATTCAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilC | Haemophilus influenzae 86-028NP |
96.798 |
100 |
0.968 |
| pilC | Haemophilus influenzae Rd KW20 |
96.552 |
100 |
0.966 |
| pilC | Glaesserella parasuis strain SC1401 |
38.404 |
98.768 |
0.379 |