Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   Hhaem_RS00620 Genome accession   NZ_AP024093
Coordinates   125992..126684 (+) Length   230 a.a.
NCBI ID   WP_223893700.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain 2019-19     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120992..131684
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Hhaem_RS00595 (Hhaem_01210) rppH 121162..121752 (-) 591 WP_118813215.1 RNA pyrophosphohydrolase -
  Hhaem_RS00600 (Hhaem_01220) ampD 122278..122832 (-) 555 WP_223893695.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  Hhaem_RS00605 (Hhaem_01230) pilA 122947..123387 (+) 441 WP_223893697.1 prepilin peptidase-dependent pilin Machinery gene
  Hhaem_RS00610 (Hhaem_01240) pilB 123384..124778 (+) 1395 WP_223893698.1 GspE/PulE family protein Machinery gene
  Hhaem_RS00615 (Hhaem_01250) pilC 124775..125995 (+) 1221 WP_223893699.1 type II secretion system F family protein Machinery gene
  Hhaem_RS00620 (Hhaem_01260) pilD 125992..126684 (+) 693 WP_223893700.1 A24 family peptidase Machinery gene
  Hhaem_RS00625 (Hhaem_01270) rho 126738..128000 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  Hhaem_RS00630 (Hhaem_01280) metJ 128248..128565 (+) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  Hhaem_RS00635 (Hhaem_01290) cueR 128579..128965 (-) 387 WP_005629546.1 Cu(I)-responsive transcriptional regulator -
  Hhaem_RS00640 (Hhaem_01300) - 129042..129248 (+) 207 WP_223893701.1 heavy-metal-associated domain-containing protein -
  Hhaem_RS00645 (Hhaem_01310) - 129223..131394 (+) 2172 WP_223893702.1 cation-translocating P-type ATPase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26695.73 Da        Isoelectric Point: 8.5725

>NTDB_id=83417 Hhaem_RS00620 WP_223893700.1 125992..126684(+) (pilD) [Haemophilus haemolyticus strain 2019-19]
MIYFAMFLLGGILGIALWFYLSDFITRLQHEIYTAYVELFPQNHSPFQLHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSILVVWLGLTLLILWAISYIDWHYQLISTTLCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWLAKFYYS
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYLVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=83417 Hhaem_RS00620 WP_223893700.1 125992..126684(+) (pilD) [Haemophilus haemolyticus strain 2019-19]
ATGATTTACTTCGCAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGATTTTATTACGCG
TTTACAGCACGAAATTTATACGGCTTACGTTGAATTATTTCCACAAAACCATTCTCCATTTCAACTGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTAGGATTTATATTTTTACAAATTGCCTTC
AAGGACTCTATTTTAGTTGTATGGCTAGGGCTCACACTTCTTATCCTTTGGGCCATTAGTTATATTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGTTACTTACTCTCGGTTTATTTGGAGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGTATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGCTTGCAAAATTCTATTACAGC
AAAGAAGCCTTTGGACGAGGCGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACTTTACCTCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGGAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTGTCGGCCGTCATCATTTATCTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae Rd KW20

91.304

100

0.913
  pilD Haemophilus influenzae 86-028NP

90

100

0.9

Multiple sequence alignment