Detailed information NTG0083053

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H7680_RS02590
• Genome accession: NZ_AP023394
• Coordinates: 491773..493926 (-)
• Length: 717 a.a.
• NCBI ID: WP_014612084.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 159
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 486773..498926

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7680_RS02570 (SDSE159_04640)	comE/blpR	488037..488786 (+)	750	WP_046159788.1	response regulator transcription factor	Regulator
H7680_RS02575 (SDSE159_04650)	-	488787..490121 (+)	1335	WP_138127997.1	GHKL domain-containing protein	-
H7680_RS02580 (SDSE159_04660)	-	490182..490307 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
H7680_RS02585 (SDSE159_04670)	-	490398..491762 (-)	1365	WP_012766651.1	bacteriocin secretion accessory protein	-
H7680_RS02590 (SDSE159_04680)	comA/nlmT	491773..493926 (-)	2154	WP_014612084.1	peptide cleavage/export ABC transporter	Regulator
H7680_RS02595 (SDSE159_04690)	-	494213..494440 (+)	228	WP_002992018.1	Blp family class II bacteriocin	-
H7680_RS02600 (SDSE159_04700)	-	494453..494653 (+)	201	WP_003060803.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
H7680_RS02605 (SDSE159_04720)	-	494948..495142 (+)	195	WP_002990768.1	hypothetical protein	-
H7680_RS02610 (SDSE159_04730)	-	495308..495742 (+)	435	WP_014612086.1	helix-turn-helix domain-containing protein	-
H7680_RS02620	-	496940..497473 (+)	534	Protein_462	IS30 family transposase	-
H7680_RS10585 (SDSE159_04760)	-	497504..497743 (+)	240	WP_014612088.1	hypothetical protein	-
H7680_RS02625 (SDSE159_04770)	-	497937..498347 (+)	411	WP_012766654.1	hypothetical protein	-
H7680_RS02630	-	498594..498841 (+)	248	Protein_465	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80532.38 Da
• Isoelectric Point: 6.8704

>NTDB_id=83053 H7680_RS02590 WP_014612084.1 491773..493926(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVNVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDTNGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=83053 H7680_RS02590 WP_014612084.1 491773..493926(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAATGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGATAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTTCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATACCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGTA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.587	99.721	0.724
comA	Streptococcus mitis NCTC 12261	67.367	99.582	0.671
comA	Streptococcus mitis SK321	66.947	99.582	0.667
comA	Streptococcus pneumoniae Rx1	66.947	99.582	0.667
comA	Streptococcus pneumoniae D39	66.947	99.582	0.667
comA	Streptococcus pneumoniae R6	66.947	99.582	0.667
comA	Streptococcus pneumoniae TIGR4	66.667	99.582	0.664
comA	Streptococcus gordonii str. Challis substr. CH1	65.738	100	0.658