Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   H7679_RS03270 Genome accession   NZ_AP023392
Coordinates   634627..635331 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain DAT300     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 629627..640331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS03250 (DAT300_05930) - 631435..632094 (-) 660 WP_024384909.1 amino acid ABC transporter permease -
  H7679_RS03255 (DAT300_05940) - 632109..632807 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  H7679_RS03260 (DAT300_05950) - 632822..633661 (-) 840 WP_105115141.1 transporter substrate-binding domain-containing protein -
  H7679_RS03265 (DAT300_05960) - 633672..634433 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  H7679_RS03270 (DAT300_05970) micA 634627..635331 (+) 705 WP_004298854.1 response regulator YycF Regulator
  H7679_RS03275 (DAT300_05980) micB 635324..636673 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H7679_RS03280 (DAT300_05990) vicX 636680..637483 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  H7679_RS03285 (DAT300_06000) vga(F) 637843..639228 (+) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=82944 H7679_RS03270 WP_004298854.1 634627..635331(+) (micA) [Streptococcus suis strain DAT300]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=82944 H7679_RS03270 WP_004298854.1 634627..635331(+) (micA) [Streptococcus suis strain DAT300]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAAACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment