Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   H7677_RS03150 Genome accession   NZ_AP023391
Coordinates   629433..630137 (+) Length   234 a.a.
NCBI ID   WP_184494091.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 624433..635137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS03130 (DAT299_05650) - 626241..626900 (-) 660 WP_105095419.1 amino acid ABC transporter permease -
  H7677_RS03135 (DAT299_05660) - 626915..627613 (-) 699 WP_014637677.1 amino acid ABC transporter permease -
  H7677_RS03140 (DAT299_05670) - 627628..628467 (-) 840 WP_184494089.1 transporter substrate-binding domain-containing protein -
  H7677_RS03145 (DAT299_05680) - 628478..629239 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  H7677_RS03150 (DAT299_05690) micA 629433..630137 (+) 705 WP_184494091.1 response regulator YycF Regulator
  H7677_RS03155 (DAT299_05700) micB 630130..631479 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H7677_RS03160 (DAT299_05710) vicX 631486..632289 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  H7677_RS03165 (DAT299_05720) - 633152..634354 (-) 1203 WP_332068681.1 IS110 family transposase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26679.68 Da        Isoelectric Point: 4.9842

>NTDB_id=82890 H7677_RS03150 WP_184494091.1 629433..630137(+) (micA) [Streptococcus suis strain DAT299]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFGAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=82890 H7677_RS03150 WP_184494091.1 629433..630137(+) (micA) [Streptococcus suis strain DAT299]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGGTATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGGGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCTTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGTTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.116

99.573

0.808
  vicR Streptococcus mutans UA159

79.574

100

0.799
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.043

98.291

0.423
  scnR Streptococcus mutans UA159

38.528

98.718

0.38

Multiple sequence alignment