Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   H7677_RS03155 Genome accession   NZ_AP023391
Coordinates   630130..631479 (+) Length   449 a.a.
NCBI ID   WP_024379730.1    Uniprot ID   A0A0Z8J8V5
Organism   Streptococcus suis strain DAT299     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 625130..636479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS03130 (DAT299_05650) - 626241..626900 (-) 660 WP_105095419.1 amino acid ABC transporter permease -
  H7677_RS03135 (DAT299_05660) - 626915..627613 (-) 699 WP_014637677.1 amino acid ABC transporter permease -
  H7677_RS03140 (DAT299_05670) - 627628..628467 (-) 840 WP_184494089.1 transporter substrate-binding domain-containing protein -
  H7677_RS03145 (DAT299_05680) - 628478..629239 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  H7677_RS03150 (DAT299_05690) micA 629433..630137 (+) 705 WP_184494091.1 response regulator YycF Regulator
  H7677_RS03155 (DAT299_05700) micB 630130..631479 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H7677_RS03160 (DAT299_05710) vicX 631486..632289 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  H7677_RS03165 (DAT299_05720) - 633152..634354 (-) 1203 WP_332068681.1 IS110 family transposase -
  H7677_RS03170 (DAT299_05730) - 634633..635166 (+) 534 WP_232088998.1 ATP-binding cassette domain-containing protein -
  H7677_RS03175 - 635142..636010 (+) 869 Protein_580 MobA/MobL family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51035.09 Da        Isoelectric Point: 4.5202

>NTDB_id=82891 H7677_RS03155 WP_024379730.1 630130..631479(+) (micB) [Streptococcus suis strain DAT299]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=82891 H7677_RS03155 WP_024379730.1 630130..631479(+) (micB) [Streptococcus suis strain DAT299]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTGGACATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATTCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCATCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAGCGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCCAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8J8V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment