Detailed information NTG0082793

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7675_RS04835
• Genome accession: NZ_AP023389
• Coordinates: 946141..946977 (-)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain KUN-0012590
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 941141..951977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7675_RS04815 (KUN2590_08970)	-	941381..942373 (-)	993	WP_031488271.1	D-lactate dehydrogenase	-
H7675_RS04820 (KUN2590_08980)	-	942388..942933 (-)	546	Protein_900	PTS sugar transporter subunit IIC	-
H7675_RS04825	-	942973..943830 (+)	858	Protein_901	LysR family transcriptional regulator	-
H7675_RS04830 (KUN2590_09000)	topA	943905..946034 (-)	2130	WP_011017773.1	type I DNA topoisomerase	-
H7675_RS04835 (KUN2590_09010)	dprA	946141..946977 (-)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
H7675_RS04840 (KUN2590_09020)	-	947042..947833 (-)	792	WP_031488275.1	ribonuclease HII	-
H7675_RS04845 (KUN2590_09030)	ylqF	947823..948671 (-)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
H7675_RS04850 (KUN2590_09040)	-	948890..949330 (+)	441	WP_031488277.1	DUF1836 domain-containing protein	-
H7675_RS04855 (KUN2590_09050)	trhA	949327..949977 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7675_RS04860 (KUN2590_09060)	-	950094..951005 (+)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
H7675_RS04865 (KUN2590_09070)	-	951055..951492 (-)	438	WP_031488279.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=82793 H7675_RS04835 WP_031488274.1 946141..946977(-) (dprA) [Streptococcus pyogenes strain KUN-0012590]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=82793 H7675_RS04835 WP_031488274.1 946141..946977(-) (dprA) [Streptococcus pyogenes strain KUN-0012590]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363