Detailed information NTG0082740

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7674_RS04805
• Genome accession: NZ_AP023388
• Coordinates: 957127..957963 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NIH35
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 952127..962963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7674_RS04785 (SPNIH35_08940)	-	952367..953359 (-)	993	WP_021340798.1	D-lactate dehydrogenase	-
H7674_RS04790 (SPNIH35_08950)	-	953374..953919 (-)	546	Protein_897	PTS sugar transporter subunit IIC	-
H7674_RS04795	-	953959..954816 (+)	858	Protein_898	LysR family transcriptional regulator	-
H7674_RS04800 (SPNIH35_08970)	topA	954891..957020 (-)	2130	WP_011284793.1	type I DNA topoisomerase	-
H7674_RS04805 (SPNIH35_08980)	dprA	957127..957963 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
H7674_RS04810 (SPNIH35_08990)	-	958028..958819 (-)	792	WP_011888871.1	ribonuclease HII	-
H7674_RS04815 (SPNIH35_09000)	ylqF	958809..959657 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
H7674_RS04820 (SPNIH35_09010)	-	959876..960316 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
H7674_RS04825 (SPNIH35_09020)	trhA	960313..960963 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7674_RS04830 (SPNIH35_09030)	-	961080..961991 (+)	912	WP_011284791.1	diacylglycerol/lipid kinase family protein	-
H7674_RS04835 (SPNIH35_09040)	-	962041..962475 (-)	435	WP_021340932.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=82740 H7674_RS04805 WP_002995009.1 957127..957963(-) (dprA) [Streptococcus pyogenes strain NIH35]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=82740 H7674_RS04805 WP_002995009.1 957127..957963(-) (dprA) [Streptococcus pyogenes strain NIH35]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367