Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   R8625_RS09920 Genome accession   NZ_AP026923
Coordinates   1889498..1890514 (-) Length   338 a.a.
NCBI ID   WP_138028521.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1884498..1895514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS09875 (PC0054_19220) - 1884897..1885124 (-) 228 WP_001125555.1 helix-turn-helix transcriptional regulator -
  R8625_RS09880 (PC0054_19240) - 1885315..1885605 (-) 291 WP_001815531.1 hypothetical protein -
  R8625_RS09885 (PC0054_19250) - 1885602..1885748 (-) 147 WP_000389580.1 hypothetical protein -
  R8625_RS09890 (PC0054_19260) - 1886143..1886265 (-) 123 WP_000343850.1 hypothetical protein -
  R8625_RS09895 (PC0054_19270) - 1886339..1886614 (-) 276 WP_001094372.1 hypothetical protein -
  R8625_RS09900 (PC0054_19280) irvR 1886789..1887595 (+) 807 WP_054422885.1 XRE family transcriptional regulator Regulator
  R8625_RS09905 (PC0054_19290) - 1887597..1887797 (+) 201 WP_000064302.1 hypothetical protein -
  R8625_RS09910 (PC0054_19300) - 1887971..1889416 (+) 1446 WP_024478469.1 recombinase family protein -
  R8625_RS09920 (PC0054_19310) comGB/cglB 1889498..1890514 (-) 1017 WP_138028521.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8625_RS09925 (PC0054_19320) comGA/cglA/cilD 1890462..1891403 (-) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  R8625_RS09930 (PC0054_19330) - 1891479..1891844 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8625_RS09935 (PC0054_19340) - 1891995..1893053 (-) 1059 WP_000649473.1 zinc-dependent alcohol dehydrogenase family protein -
  R8625_RS09940 (PC0054_19350) nagA 1893216..1894367 (-) 1152 WP_001134454.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38585.65 Da        Isoelectric Point: 9.7316

>NTDB_id=82487 R8625_RS09920 WP_138028521.1 1889498..1890514(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900700054]
MDISQVFRLRRKKLATAKQKNIITLFNNFFSSGFHLVETISFLDRSALLDKQCVTRMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=82487 R8625_RS09920 WP_138028521.1 1889498..1890514(-) (comGB/cglB) [Streptococcus pneumoniae strain PZ900700054]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATTTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCGGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGTTTTTTCTTCTCTTAATCATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGCAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAATGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATTTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

97.929

100

0.979
  comGB/cglB Streptococcus pneumoniae D39

97.929

100

0.979
  comGB/cglB Streptococcus pneumoniae R6

97.929

100

0.979
  comGB/cglB Streptococcus pneumoniae TIGR4

97.929

100

0.979
  comGB/cglB Streptococcus mitis SK321

94.083

100

0.941
  comGB/cglB Streptococcus mitis NCTC 12261

93.491

100

0.935
  comGB Streptococcus gordonii str. Challis substr. CH1

69.94

99.408

0.695
  comGB Streptococcus mutans UA140

57.729

93.787

0.541
  comGB Streptococcus mutans UA159

57.729

93.787

0.541
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5

Multiple sequence alignment