Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   M2Y46_RS00725 Genome accession   NZ_AP023347
Coordinates   152059..152802 (+) Length   247 a.a.
NCBI ID   WP_096465473.1    Uniprot ID   -
Organism   Helicobacter pylori strain JSHR6     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 147059..157802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2Y46_RS00700 (JSHR6_01370) panD 149211..149567 (+) 357 WP_212793455.1 aspartate 1-decarboxylase -
  M2Y46_RS00705 (JSHR6_01380) - 149570..149863 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  M2Y46_RS00710 (JSHR6_01390) - 149863..150858 (+) 996 WP_248415724.1 PDZ domain-containing protein -
  M2Y46_RS00715 (JSHR6_01400) comB6 150866..151921 (+) 1056 WP_180621765.1 P-type conjugative transfer protein TrbL Machinery gene
  M2Y46_RS00720 comB7 151937..152062 (+) 126 WP_024117273.1 hypothetical protein Machinery gene
  M2Y46_RS00725 (JSHR6_01410) comB8 152059..152802 (+) 744 WP_096465473.1 virB8 family protein Machinery gene
  M2Y46_RS00730 (JSHR6_01420) comB9 152802..153770 (+) 969 WP_248415465.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  M2Y46_RS00735 (JSHR6_01430) comB10 153763..154899 (+) 1137 WP_248415466.1 DNA type IV secretion system protein ComB10 Machinery gene
  M2Y46_RS00740 (JSHR6_01440) - 154969..156381 (+) 1413 WP_248415467.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  M2Y46_RS00745 (JSHR6_01450) gmd 156395..157540 (+) 1146 WP_248415468.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28670.89 Da        Isoelectric Point: 8.9546

>NTDB_id=82487 M2Y46_RS00725 WP_096465473.1 152059..152802(+) (comB8) [Helicobacter pylori strain JSHR6]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSVAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=82487 M2Y46_RS00725 WP_096465473.1 152059..152802(+) (comB8) [Helicobacter pylori strain JSHR6]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTAATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGTGT
TTCTGTTGCAGCTAAACTCATGAATGAAAACAAACTAGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment