Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   R8625_RS09925 Genome accession   NZ_AP026923
Coordinates   1890462..1891403 (-) Length   313 a.a.
NCBI ID   WP_016398028.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1885462..1896403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS09885 (PC0054_19250) - 1885602..1885748 (-) 147 WP_000389580.1 hypothetical protein -
  R8625_RS09890 (PC0054_19260) - 1886143..1886265 (-) 123 WP_000343850.1 hypothetical protein -
  R8625_RS09895 (PC0054_19270) - 1886339..1886614 (-) 276 WP_001094372.1 hypothetical protein -
  R8625_RS09900 (PC0054_19280) irvR 1886789..1887595 (+) 807 WP_054422885.1 XRE family transcriptional regulator Regulator
  R8625_RS09905 (PC0054_19290) - 1887597..1887797 (+) 201 WP_000064302.1 hypothetical protein -
  R8625_RS09910 (PC0054_19300) - 1887971..1889416 (+) 1446 WP_024478469.1 recombinase family protein -
  R8625_RS09920 (PC0054_19310) comGB/cglB 1889498..1890514 (-) 1017 WP_138028521.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8625_RS09925 (PC0054_19320) comGA/cglA/cilD 1890462..1891403 (-) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  R8625_RS09930 (PC0054_19330) - 1891479..1891844 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8625_RS09935 (PC0054_19340) - 1891995..1893053 (-) 1059 WP_000649473.1 zinc-dependent alcohol dehydrogenase family protein -
  R8625_RS09940 (PC0054_19350) nagA 1893216..1894367 (-) 1152 WP_001134454.1 N-acetylglucosamine-6-phosphate deacetylase -
  R8625_RS09945 (PC0054_19360) - 1894520..1896337 (-) 1818 WP_317649173.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35546.46 Da        Isoelectric Point: 6.0083

>NTDB_id=82488 R8625_RS09925 WP_016398028.1 1890462..1891403(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PZ900700054]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=82488 R8625_RS09925 WP_016398028.1 1890462..1891403(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PZ900700054]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.681

100

0.997
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.681

100

0.997
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.681

100

0.997
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.681

100

0.997
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.166

100

0.962
  comGA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comGA Streptococcus mutans UA159

65.916

99.361

0.655
  comGA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.642

84.665

0.361

Multiple sequence alignment