Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   R8625_RS09900 Genome accession   NZ_AP026923
Coordinates   1886789..1887595 (+) Length   268 a.a.
NCBI ID   WP_054422885.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1881789..1892595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS09840 (PC0054_19140) - 1881867..1882097 (-) 231 WP_000192920.1 hypothetical protein -
  R8625_RS09845 (PC0054_19150) - 1882217..1882360 (-) 144 WP_000196747.1 hypothetical protein -
  R8625_RS09850 (PC0054_19160) - 1882353..1882607 (-) 255 WP_317649171.1 hypothetical protein -
  R8625_RS09855 (PC0054_19170) - 1882600..1882806 (-) 207 WP_317649172.1 hypothetical protein -
  R8625_RS09860 (PC0054_19180) - 1882806..1882967 (-) 162 WP_000823399.1 BOW99_gp33 family protein -
  R8625_RS09865 (PC0054_19200) - 1883185..1884039 (-) 855 WP_001198473.1 ATP-binding protein -
  R8625_RS09870 (PC0054_19210) - 1884049..1884900 (-) 852 WP_050167223.1 DnaD domain protein -
  R8625_RS09875 (PC0054_19220) - 1884897..1885124 (-) 228 WP_001125555.1 helix-turn-helix transcriptional regulator -
  R8625_RS09880 (PC0054_19240) - 1885315..1885605 (-) 291 WP_001815531.1 hypothetical protein -
  R8625_RS09885 (PC0054_19250) - 1885602..1885748 (-) 147 WP_000389580.1 hypothetical protein -
  R8625_RS09890 (PC0054_19260) - 1886143..1886265 (-) 123 WP_000343850.1 hypothetical protein -
  R8625_RS09895 (PC0054_19270) - 1886339..1886614 (-) 276 WP_001094372.1 hypothetical protein -
  R8625_RS09900 (PC0054_19280) irvR 1886789..1887595 (+) 807 WP_054422885.1 XRE family transcriptional regulator Regulator
  R8625_RS09905 (PC0054_19290) - 1887597..1887797 (+) 201 WP_000064302.1 hypothetical protein -
  R8625_RS09910 (PC0054_19300) - 1887971..1889416 (+) 1446 WP_024478469.1 recombinase family protein -
  R8625_RS09920 (PC0054_19310) comGB/cglB 1889498..1890514 (-) 1017 WP_138028521.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8625_RS09925 (PC0054_19320) comGA/cglA/cilD 1890462..1891403 (-) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  R8625_RS09930 (PC0054_19330) - 1891479..1891844 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 268 a.a.        Molecular weight: 30263.60 Da        Isoelectric Point: 4.4747

>NTDB_id=82486 R8625_RS09900 WP_054422885.1 1886789..1887595(+) (irvR) [Streptococcus pneumoniae strain PZ900700054]
MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIPPSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPR
FVTNNSMVDDSSSNTSSIQTIYDQLERPRQGKVLNYAERQLKEQRNEEETKINEVSENIIRLDDYRQATYRRVTGVVSAG
SGSIQDDDLDMEVSFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVDGANYVKKLRQGYLESL
NPDYEDIHLDESNDIRTIGEVVSVYREK

Nucleotide


Download         Length: 807 bp        

>NTDB_id=82486 R8625_RS09900 WP_054422885.1 1886789..1887595(+) (irvR) [Streptococcus pneumoniae strain PZ900700054]
ATGGCAAGAGGACGAGGAAAATTAACTCCTCAAGATAAAGAGGATATGAAAGTCTTTTCCGCAAATCTTAACTCAATTTT
ATCTGATAGAAATTGTAAACAAGCTGAGCTATCTCGAGCGACAGGAATACCACCTAGCACATTGACAGGGTATGTAAAAG
GAACTTCTTTGCCAATCCCTGGCAATGTTCAAAAAATTGCAGATTTTTTTGGAGTACCTAAATCTGTATTAGACCCTAGA
TTTGTAACTAATAATTCTATGGTCGATGACTCTTCTTCTAATACTTCCTCTATCCAAACCATCTACGACCAACTAGAACG
ACCTAGACAGGGCAAAGTCCTGAATTATGCAGAGAGGCAACTGAAAGAGCAGAGGAACGAAGAAGAAACGAAGATAAACG
AAGTATCGGAGAACATCATCAGACTGGACGACTACAGACAGGCTACTTACCGACGTGTTACTGGGGTTGTCTCTGCTGGT
AGTGGTTCGATACAGGACGACGATTTAGATATGGAGGTTTCGTTCTATGAGGATGAAATCCCAGACGACTACGACGCTAT
CGCTTATGTCGTCGGCAACTCTATGGAGCCAAAGATAAAGAATGGTGACTATCTTTTTATAAAGAATACCCAACAGGTTG
ATTATAACACTATCGGCATCTTCCAAGTAGACGGCGCTAACTATGTTAAGAAACTGCGTCAGGGATATCTGGAAAGCTTG
AATCCAGATTATGAGGATATACACCTAGACGAAAGCAACGACATCCGAACTATTGGGGAAGTTGTCAGTGTGTATAGGGA
GAAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(30-74)

Peptidase S24-like (Peptidase_S24)

(155-262)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.614

100

0.437

Multiple sequence alignment