Detailed information NTG0822809

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: R6Y88_RS11335
• Genome accession: NZ_CP137687
• Coordinates: 2220928..2222130 (+)
• Length: 400 a.a.
• NCBI ID: WP_021481077.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain YT-4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2215928..2227130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6Y88_RS11315	walK	2216009..2217844 (+)	1836	WP_009968432.1	cell wall metabolism sensor histidine kinase WalK	-
R6Y88_RS11320	walH	2217834..2219201 (+)	1368	WP_041518280.1	WalRK two-component regulatory system regulator WalH	-
R6Y88_RS11325	walI	2219188..2220030 (+)	843	WP_003244037.1	WalRK two-component regulatory system regulator WalI	-
R6Y88_RS11330	vicX	2220052..2220846 (+)	795	WP_015483958.1	MBL fold metallo-hydrolase	Regulator
R6Y88_RS11335	htrA	2220928..2222130 (+)	1203	WP_021481077.1	serine protease HtrC	Regulator
R6Y88_RS11340	-	2222150..2222276 (+)	127	Protein_2177	hypothetical protein	-
R6Y88_RS11345	-	2222389..2222577 (+)	189	Protein_2178	ATP-binding protein	-
R6Y88_RS11350	rocR	2222559..2223944 (-)	1386	WP_015385164.1	arginine utilization regulatory protein RocR	-
R6Y88_RS11355	rocD	2224185..2225390 (+)	1206	WP_015483955.1	ornithine aminotransferase	-
R6Y88_RS11360	rocE	2225613..2227016 (+)	1404	WP_015483954.1	amino acid permease	-

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 42756.50 Da
• Isoelectric Point: 5.3354

>NTDB_id=822809 R6Y88_RS11335 WP_021481077.1 2220928..2222130(+) (htrA) [Bacillus subtilis strain YT-4]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide

• Length: 1203 bp

>NTDB_id=822809 R6Y88_RS11335 WP_021481077.1 2220928..2222130(+) (htrA) [Bacillus subtilis strain YT-4]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTATCTTTCAAATGAAGGGCTGGATACGGGCG
CTTTAGATCAGCAGCAGAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAATCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (295-392)

• Peptidase family M50 (Peptidase_M50) (185-395)

• Trypsin-like peptidase domain (Trypsin_2) (110-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	43.829	99.25	0.435
htrA	Streptococcus gordonii str. Challis substr. CH1	41.542	100	0.417
htrA	Streptococcus mitis NCTC 12261	43.005	96.5	0.415
htrA	Streptococcus pneumoniae TIGR4	45.152	82.5	0.373
htrA	Streptococcus pneumoniae D39	45.152	82.5	0.373
htrA	Streptococcus pneumoniae Rx1	45.152	82.5	0.373
htrA	Streptococcus pneumoniae R6	45.152	82.5	0.373