Detailed information NTG0819083

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO18_RS10275
• Genome accession: NZ_CP123121
• Coordinates: 2102481..2103368 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GE-MSSA38
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2097481..2108368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO18_RS10245 (QAO18_10220)	-	2098212..2098973 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO18_RS10250 (QAO18_10225)	-	2099219..2099674 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO18_RS10255 (QAO18_10230)	-	2099796..2099897 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO18_RS10260 (QAO18_10235)	-	2099957..2101381 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO18_RS10265 (QAO18_10240)	-	2101579..2101779 (+)	201	WP_000604723.1	hypothetical protein	-
QAO18_RS10270 (QAO18_10245)	braR	2101805..2102470 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO18_RS10275 (QAO18_10250)	braS	2102481..2103368 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO18_RS10280 (QAO18_10255)	-	2103476..2104231 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
QAO18_RS10285 (QAO18_10260)	-	2104228..2106228 (+)	2001	WP_000776746.1	ABC transporter permease	-
QAO18_RS10290 (QAO18_10265)	-	2106892..2107005 (+)	114	WP_072384844.1	hypothetical protein	-
QAO18_RS10295 (QAO18_10270)	-	2107387..2107647 (+)	261	WP_072434822.1	hypothetical protein	-
QAO18_RS10300 (QAO18_10275)	-	2107657..2108154 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO18_RS10305 (QAO18_10280)	-	2108262..2108350 (-)	89	Protein_1995	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=819083 QAO18_RS10275 WP_000143420.1 2102481..2103368(+) (braS) [Staphylococcus aureus strain GE-MSSA38]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819083 QAO18_RS10275 WP_000143420.1 2102481..2103368(+) (braS) [Staphylococcus aureus strain GE-MSSA38]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993