Detailed information NTG0816069

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: R1Y14_RS07565
• Genome accession: NZ_CP136899
• Coordinates: 1477726..1478574 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705302.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ST62
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1472726..1483574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R1Y14_RS07555 (R1Y14_07555)	-	1474554..1475597 (-)	1044	WP_001812710.1	TIGR00341 family protein	-
R1Y14_RS07560 (R1Y14_07560)	-	1476201..1477154 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
R1Y14_RS07565 (R1Y14_07565)	dprA/cilB/dalA	1477726..1478574 (-)	849	WP_000705302.1	DNA-processing protein DprA	Machinery gene
R1Y14_RS07570 (R1Y14_07570)	-	1478671..1479360 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
R1Y14_RS07575 (R1Y14_07575)	-	1479372..1480250 (-)	879	WP_000837609.1	DMT family transporter	-
R1Y14_RS07580 (R1Y14_07580)	licA	1480240..1481109 (-)	870	WP_000411205.1	choline kinase LicA	-
R1Y14_RS07585 (R1Y14_07585)	-	1481126..1482148 (-)	1023	WP_000609894.1	ribitol-5-phosphate dehydrogenase	-
R1Y14_RS07590 (R1Y14_07590)	-	1482153..1482860 (-)	708	WP_000638501.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31090.78 Da
• Isoelectric Point: 5.4047

>NTDB_id=816069 R1Y14_RS07565 WP_000705302.1 1477726..1478574(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain ST62]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPASILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=816069 R1Y14_RS07565 WP_000705302.1 1477726..1478574(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain ST62]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGCTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGCTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55	99.291	0.546
dprA	Staphylococcus aureus N315	37.102	100	0.372