Detailed information NTG0812239

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: P8P68_RS06925
• Genome accession: NZ_CP121467
• Coordinates: 1419386..1421539 (-)
• Length: 717 a.a.
• NCBI ID: WP_278275805.1
• Uniprot ID: -
• Organism: Streptococcus sp. D7B5
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1414386..1426539

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8P68_RS06915 (P8P68_06915)	purC	1417148..1417855 (-)	708	WP_000043285.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
P8P68_RS06920 (P8P68_06920)	comB	1418024..1419373 (-)	1350	WP_278275804.1	competence pheromone export protein ComB	Regulator
P8P68_RS06925 (P8P68_06925)	comA	1419386..1421539 (-)	2154	WP_278275805.1	peptide cleavage/export ABC transporter ComA	Regulator
P8P68_RS06930 (P8P68_06930)	-	1421703..1421898 (-)	196	Protein_1320	hypothetical protein	-
P8P68_RS06935 (P8P68_06935)	-	1421900..1422109 (-)	210	WP_070696356.1	bacteriocin immunity protein	-
P8P68_RS06940 (P8P68_06940)	-	1422134..1422322 (-)	189	WP_000722236.1	hypothetical protein	-
P8P68_RS06945 (P8P68_06945)	-	1422332..1422499 (-)	168	WP_278275806.1	bacteriocin	-
P8P68_RS06950 (P8P68_06950)	-	1422517..1422705 (-)	189	WP_049501355.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
P8P68_RS06955 (P8P68_06955)	-	1423017..1423253 (-)	237	WP_000136435.1	acyl carrier protein	-
P8P68_RS06960 (P8P68_06960)	plsX	1423259..1424251 (-)	993	WP_278275807.1	phosphate acyltransferase PlsX	-
P8P68_RS06965 (P8P68_06965)	recO	1424248..1425018 (-)	771	WP_049478102.1	DNA repair protein RecO	-
P8P68_RS06970 (P8P68_06970)	-	1425015..1426184 (-)	1170	WP_049479245.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80494.83 Da
• Isoelectric Point: 7.3419

>NTDB_id=812239 P8P68_RS06925 WP_278275805.1 1419386..1421539(-) (comA) [Streptococcus sp. D7B5]
MKFRKRHYRPQVDQMDCGVASLAMIFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAQEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPNYKPHREKKQGLLSFLPI
LFKQRGLIANIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETVKSLTSESQRYQKIDKEFVAYLKKSFAYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGEMTFKQVHYKYGYGRDVLSDINLTIPQGSKIAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMTLDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGTPADLLAQDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=812239 P8P68_RS06925 WP_278275805.1 1419386..1421539(-) (comA) [Streptococcus sp. D7B5]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCCTTGGCTATGATCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCATCTAAGAGAACTAGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCACAGGAAATTGGTTTTGAAACGCGAGCTATCAAGGCGGATATGACGCTCTTTGATCTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGGAAATTGCTCCACTATTATGTGGTGATAGGTCAGGATAAAAAGCA
CATTCATATCGCTGATCCGGATCCTGGTGTCAAGCTGACTAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGAG
TCAGTCTCTTTATGGCTCCGTCTCCAAACTATAAACCCCACAGGGAGAAAAAACAAGGACTCTTATCCTTCTTGCCAATC
TTGTTCAAACAGCGGGGCTTGATTGCTAATATCGTTTTGGCAACACTTTTGGTAACCCTGATCAATATCGTGGGCTCCTA
CTATCTGCAGTCCATCATTGATAGTTACGTACCAGACCAGATGCGTTCGACCTTGGGCATCATCTCAATAGGACTAGTCA
TCGTCTATATTCTCCAGCAGATTTTGTCTTATGCGCAGGAATACCTCTTACTTGTTCTGGGTCAACGGTTGTCCATCGAT
GTGATTTTGTCCTACATCAAGCATGTTTTTCATCTGCCGATGTCCTTTTTCGCGACACGCAGGACAGGAGAAATCGTGTC
TCGTTTCACGGATGCTAACAGTATCATTGACGCGCTAGCTTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTTGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTACTTGCGCTTCCTATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCTAATGCGGTTCTGTCTTCTTCTAT
TATCGAGGACATCAACGGTATTGAGACTGTTAAATCTTTGACCAGTGAAAGTCAGCGTTACCAAAAGATTGACAAGGAAT
TTGTAGCTTATCTGAAAAAATCCTTTGCCTATAGTCGGGCAGAAAGTCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTGGGAGCTATTCTTGTCATGGATGGAAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGTCTGAACGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTAGAAGATTTGAGCATGATG
AAGGGAGAGATGACCTTCAAGCAGGTTCACTACAAGTATGGCTATGGTCGTGACGTCTTGTCGGATATCAATTTGACCAT
TCCACAAGGGTCTAAGATAGCTTTTGTGGGGATTTCAGGTTCGGGTAAGACCACCTTAGCCAAAATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGACAAAAAGGCTTTGCGTCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGAGCAGTCGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCTCTGAATTATCAGACAG
AATTGACTTCGGATGGGGCTGGAATTTCAGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGACGAGGCGACCAGCAGTCTGGATATCTTGACAGAGAAGCGGATCGTGGATAATCTCATGACACT
AGACAAGACCCTTATTTTCATCGCCCACCGCTTGACCATCGCTGAGCGGACAGAGAAGGTTGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGCACCCCTGCAGACTTGCTTGCACAGGATGGCTTTTATGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	94.282	100	0.943
comA	Streptococcus mitis SK321	94.003	100	0.94
comA	Streptococcus pneumoniae Rx1	94.003	100	0.94
comA	Streptococcus pneumoniae D39	94.003	100	0.94
comA	Streptococcus pneumoniae R6	94.003	100	0.94
comA	Streptococcus pneumoniae TIGR4	93.584	100	0.936
comA	Streptococcus gordonii str. Challis substr. CH1	80.474	100	0.805
comA/nlmT	Streptococcus mutans UA159	64.156	100	0.642