Detailed information NTG0812217

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: P8P68_RS05210
• Genome accession: NZ_CP121467
• Coordinates: 1056271..1058424 (+)
• Length: 717 a.a.
• NCBI ID: WP_070800392.1
• Uniprot ID: -
• Organism: Streptococcus sp. D7B5
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1051271..1063424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8P68_RS05165 (P8P68_05165)	-	1051528..1051737 (-)	210	WP_049537864.1	Blp family class II bacteriocin	-
P8P68_RS05170 (P8P68_05170)	-	1051753..1052001 (-)	249	Protein_998	Blp family class II bacteriocin	-
P8P68_RS05175 (P8P68_05175)	-	1052245..1052448 (-)	204	WP_001099737.1	Blp family class II bacteriocin	-
P8P68_RS05180 (P8P68_05180)	blpM	1052464..1052718 (-)	255	WP_000379951.1	two-peptide bacteriocin subunit BlpM	-
P8P68_RS05185 (P8P68_05185)	-	1052969..1053994 (-)	1026	WP_070800394.1	thioredoxin domain-containing protein	-
P8P68_RS05190 (P8P68_05190)	-	1054154..1054528 (-)	375	WP_125384985.1	immunity protein	-
P8P68_RS05195 (P8P68_05195)	-	1054588..1054908 (-)	321	WP_000645118.1	hypothetical protein	-
P8P68_RS05200 (P8P68_05200)	-	1054923..1055150 (-)	228	WP_247924455.1	bacteriocin class II family protein	-
P8P68_RS05205 (P8P68_05205)	-	1055759..1055989 (-)	231	WP_247924443.1	bacteriocin class II family protein	-
P8P68_RS05210 (P8P68_05210)	comA/nlmT	1056271..1058424 (+)	2154	WP_070800392.1	peptide cleavage/export ABC transporter BlpA	Regulator
P8P68_RS05215 (P8P68_05215)	-	1058435..1059796 (+)	1362	WP_278275714.1	bacteriocin secretion accessory protein	-
P8P68_RS05220 (P8P68_05220)	blpC	1059853..1060008 (+)	156	WP_000360258.1	quorum-sensing system pheromone BlpC	-
P8P68_RS05225 (P8P68_05225)	-	1060051..1061391 (-)	1341	WP_221161141.1	sensor histidine kinase	-
P8P68_RS05230 (P8P68_05230)	comE/blpR	1061405..1062142 (-)	738	WP_070800389.1	LytTR family DNA-binding domain-containing protein	Regulator
P8P68_RS05235 (P8P68_05235)	-	1062147..1062485 (-)	339	WP_247924444.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
P8P68_RS05240 (P8P68_05240)	-	1062764..1063093 (+)	330	WP_084940459.1	helicase BlpT	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80797.80 Da
• Isoelectric Point: 7.6427

>NTDB_id=812217 P8P68_RS05210 WP_070800392.1 1056271..1058424(+) (comA/nlmT) [Streptococcus sp. D7B5]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAANEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQAMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLTKYSILQTNLKQGTKL
VLNIFILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENSVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKEGDKVSLVGVSGSGKTTLAKMIVNFFDPYKGQITINHQDIKNIDKKILRRHI
NYLPQQAYIFNGSILENLTLGGNSMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSALDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELIQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=812217 P8P68_RS05210 WP_070800392.1 1056271..1058424(+) (comA/nlmT) [Streptococcus sp. D7B5]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCCAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCAAATGAAATGGGTTTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATTGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGATCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTGAGCTTCCTACCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTAGTCACTATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATTATCTCAATTGGTCTAATTA
TCACCTATATCCTCCAACAAGCCATGAGCTTCTCCAGAGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGTATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCTAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTCGATTATTTGGAAAAATCCTTTAAACTTACTAAATATTCTATTTTACAAACTAATTTAAAACAAGGAACAAAGTTA
GTTCTTAATATCTTTATCCTATGGTTTGGGGCTCAATTAGTTATGTCTAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTTGAATCTGAATTTCAAGTTCAAGAAAACTCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATCAATCTAACAAT
TAAAGAAGGTGATAAGGTTAGCCTGGTTGGAGTTAGTGGTTCTGGTAAAACAACTCTAGCCAAAATGATTGTCAATTTCT
TTGACCCTTACAAAGGACAGATTACCATCAATCATCAGGATATTAAAAATATTGATAAAAAAATCTTGCGACGTCATATT
AATTACCTGCCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACCTTGGGCGGTAATAGTATGATTAG
CCAAGAAGATATTCTAAAAGCTTGCGAATTAGCTGAAATCCGTCAAGATATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGTGCTCTCGATGTTTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGGACTAACCGTGTCATTGTTCTTGACCAAGGGA
AAATCATTGAAGTTGGTAGTCATCAAGAGTTAATACAGGCGCAAGGCTTCTACCATCATCTATTCAACAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.888	99.721	0.717
comA	Streptococcus mitis NCTC 12261	66.199	99.442	0.658
comA	Streptococcus gordonii str. Challis substr. CH1	65.46	100	0.656
comA	Streptococcus pneumoniae Rx1	65.638	99.442	0.653
comA	Streptococcus pneumoniae D39	65.638	99.442	0.653
comA	Streptococcus pneumoniae R6	65.638	99.442	0.653
comA	Streptococcus mitis SK321	65.638	99.442	0.653
comA	Streptococcus pneumoniae TIGR4	65.358	99.442	0.65