Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   P8P68_RS05230 Genome accession   NZ_CP121467
Coordinates   1061405..1062142 (-) Length   245 a.a.
NCBI ID   WP_070800389.1    Uniprot ID   -
Organism   Streptococcus sp. D7B5     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1056405..1067142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS05215 (P8P68_05215) - 1058435..1059796 (+) 1362 WP_278275714.1 bacteriocin secretion accessory protein -
  P8P68_RS05220 (P8P68_05220) blpC 1059853..1060008 (+) 156 WP_000360258.1 quorum-sensing system pheromone BlpC -
  P8P68_RS05225 (P8P68_05225) - 1060051..1061391 (-) 1341 WP_221161141.1 sensor histidine kinase -
  P8P68_RS05230 (P8P68_05230) comE/blpR 1061405..1062142 (-) 738 WP_070800389.1 LytTR family DNA-binding domain-containing protein Regulator
  P8P68_RS05235 (P8P68_05235) - 1062147..1062485 (-) 339 WP_247924444.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  P8P68_RS05240 (P8P68_05240) - 1062764..1063093 (+) 330 WP_084940459.1 helicase BlpT -
  P8P68_RS05245 (P8P68_05245) - 1063155..1064204 (-) 1050 WP_278275715.1 ABC transporter permease -
  P8P68_RS05250 (P8P68_05250) pptA 1064201..1064932 (-) 732 WP_101800368.1 ABC transporter ATP-binding protein Regulator
  P8P68_RS05255 (P8P68_05255) - 1065000..1065410 (+) 411 WP_125384974.1 HIT family protein -
  P8P68_RS05260 (P8P68_05260) - 1065420..1065698 (+) 279 WP_125384973.1 hypothetical protein -
  P8P68_RS05265 (P8P68_05265) - 1065768..1066421 (+) 654 WP_278275716.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28783.95 Da        Isoelectric Point: 6.0460

>NTDB_id=812218 P8P68_RS05230 WP_070800389.1 1061405..1062142(-) (comE/blpR) [Streptococcus sp. D7B5]
MRIFVLEDDFSQQARIETTIEKLLKEHHIIPSSFEVFGKPDQLLAEMHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKSLSAEEFESRIETALLYADSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=812218 P8P68_RS05230 WP_070800389.1 1061405..1062142(-) (comE/blpR) [Streptococcus sp. D7B5]
ATGAGAATATTTGTTTTAGAAGATGATTTCTCCCAACAAGCTAGGATTGAAACGACGATTGAGAAACTCTTGAAAGAACA
TCATATCATTCCCAGCTCTTTTGAAGTCTTTGGCAAGCCAGACCAACTTCTGGCAGAGATGCATGAGAAGGGAGCACATC
AGCTATTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAAGGCCTAGAAGTGGCAAGAAAGATTCGGGATCGAGAT
CCTTATGCCCTGATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGTCCTTGTCGGCAGAGGAGTTTGAGTCTCGTATCGAGACAGCTCTTCTCTATGCCGATAGTCAAGACA
GCAAAAGCCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCTCCTAGAGCCCATCGTGTTATTCTCTATACCAAGACGGATAGGCTGGAATTTACGGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGTCATCGTTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTTAGGGAAGTTTCTGAGGCT
ATCAATAATTTGCATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.132

98.776

0.535
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38
  comE Streptococcus infantis strain Atu-4

36.179

100

0.363