NTDB

Overview

Name	micA	Type	Regulator
Locus tag	P8P68_RS02585	Genome accession	NZ_CP121467
Coordinates	542499..543206 (-)	Length	235 a.a.
NCBI ID	WP_000722057.1	Uniprot ID	A0AAX3TLC2
Organism	Streptococcus sp. D7B5
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 537499..548206

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8P68_RS02565 (P8P68_02565)	-	539100..539447 (+)	348	WP_000434660.1	thioredoxin	-
P8P68_RS02570 (P8P68_02570)	-	539458..540258 (-)	801	WP_278276105.1	potassium channel family protein	-
P8P68_RS02575 (P8P68_02575)	vicX	540346..541155 (-)	810	WP_070838541.1	MBL fold metallo-hydrolase	Regulator
P8P68_RS02580 (P8P68_02580)	micB	541157..542506 (-)	1350	WP_070800488.1	cell wall metabolism sensor histidine kinase VicK	Regulator
P8P68_RS02585 (P8P68_02585)	micA	542499..543206 (-)	708	WP_000722057.1	response regulator YycF	Regulator
P8P68_RS02590 (P8P68_02590)	mutY	543266..544441 (-)	1176	WP_216732761.1	A/G-specific adenine glycosylase	-
P8P68_RS02595 (P8P68_02595)	pta	544524..545498 (-)	975	WP_216732762.1	phosphate acetyltransferase	-
P8P68_RS02600 (P8P68_02600)	-	545542..546438 (-)	897	WP_278276106.1	RluA family pseudouridine synthase	-
P8P68_RS02605 (P8P68_02605)	-	546435..547253 (-)	819	WP_268720823.1	NAD kinase	-
P8P68_RS02610 (P8P68_02610)	-	547237..547908 (-)	672	WP_000151560.1	GTP pyrophosphokinase family protein	-

Sequence

Protein

Download Length: 235 a.a. Molecular weight: 26991.83 Da Isoelectric Point: 4.6177

                                >NTDB_id=812207 P8P68_RS02585 WP_000722057.1 542499..543206(-) (micA) [Streptococcus sp. D7B5]

MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA

KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKSQPLQIGDLEIVPDAYVAKKYGEELDL

THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide

Download Length: 708 bp

                                >NTDB_id=812207 P8P68_RS02585 WP_000722057.1 542499..543206(-) (micA) [Streptococcus sp. D7B5]

ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAAGAAGGCTACGA

AGTTGTAACAGCCTTCAACGGTCGTGAGGCAATCGAGCTATTTGAAGCTGAGCAACCCGACATTATTATCCTAGACTTGA

TGCTACCTGAAATTGATGGTTTAGAAGTAGCCAAAGCCATTCGCAAGACCAGTAGTGTTCCTATCATTATGCTCTCAGCT

AAGGATAGCGAGTTTGACAAGGTTATCGGTTTGGAACTAGGGGCAGATGATTATGTCACAAAGCCCTTCTCAAATCGTGA

ATTGCAGGCGCGTGTCAAGGCTTTACTTCGCCGTACCGACTTGGTTTCAGTTGATAGTCAAGAGTCTGATGAGAAGAAAT

CCCAGCCACTTCAGATTGGCGATTTGGAAATTGTTCCAGACGCTTACGTGGCCAAAAAATACGGTGAGGAATTAGATTTG

ACCCACCGTGAGTTTGAGCTCTTATATCACTTGGCTTCCCATATTGGACAAGTGATTACGCGTGAACACTTGCTTGAGAC

TGTTTGGGGTTATGATTATTTTGGTGATGTTCGTACAGTGGACGTGACCATCAGACGTTTGCGTGAAAAAATTGAAGATA

CTCCAAGCCGTCCAGAGTATATCCTCACCCGTCGTGGTGTTGGCTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
micA	Streptococcus pneumoniae Cp1015	92.308	99.574	0.919
vicR	Streptococcus mutans UA159	77.447	100	0.774
covR	Streptococcus salivarius strain HSISS4	43.723	98.298	0.43
covR	Lactococcus lactis subsp. lactis strain DGCC12653	43.29	98.298	0.426
scnR	Streptococcus mutans UA159	37.179	99.574	0.37

Detailed information NTG0812207