Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   P8P68_RS02580 Genome accession   NZ_CP121467
Coordinates   541157..542506 (-) Length   449 a.a.
NCBI ID   WP_070800488.1    Uniprot ID   -
Organism   Streptococcus sp. D7B5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 536157..547506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS02560 (P8P68_02560) - 537270..538988 (+) 1719 WP_278276104.1 phospho-sugar mutase -
  P8P68_RS02565 (P8P68_02565) - 539100..539447 (+) 348 WP_000434660.1 thioredoxin -
  P8P68_RS02570 (P8P68_02570) - 539458..540258 (-) 801 WP_278276105.1 potassium channel family protein -
  P8P68_RS02575 (P8P68_02575) vicX 540346..541155 (-) 810 WP_070838541.1 MBL fold metallo-hydrolase Regulator
  P8P68_RS02580 (P8P68_02580) micB 541157..542506 (-) 1350 WP_070800488.1 cell wall metabolism sensor histidine kinase VicK Regulator
  P8P68_RS02585 (P8P68_02585) micA 542499..543206 (-) 708 WP_000722057.1 response regulator YycF Regulator
  P8P68_RS02590 (P8P68_02590) mutY 543266..544441 (-) 1176 WP_216732761.1 A/G-specific adenine glycosylase -
  P8P68_RS02595 (P8P68_02595) pta 544524..545498 (-) 975 WP_216732762.1 phosphate acetyltransferase -
  P8P68_RS02600 (P8P68_02600) - 545542..546438 (-) 897 WP_278276106.1 RluA family pseudouridine synthase -
  P8P68_RS02605 (P8P68_02605) - 546435..547253 (-) 819 WP_268720823.1 NAD kinase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51603.00 Da        Isoelectric Point: 4.6091

>NTDB_id=812206 P8P68_RS02580 WP_070800488.1 541157..542506(-) (micB) [Streptococcus sp. D7B5]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNISNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDDYELRDLITQIPE
LMIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNASTQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=812206 P8P68_RS02580 WP_070800488.1 541157..542506(-) (micB) [Streptococcus sp. D7B5]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGTGATTTTATCTTTATCTTGATTTTACTTGGCTTTATCTTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTACAAGGCAGTACAGAAATCACCAATATTAGCAATAACCTCAATGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAAAGACTGCATAGTATTCTTTCTTACATGACAGATGGAGT
GCTTGCGACCAATCGCCGTGGTCAAATTACCATGATTAATGACATGGCTAAGAAACAATTAGGTGTGCAGAAAGAAGATG
TCCTTAACAAAAGCATTTTAGAATTGCTTAAGATAGAGGATGATTATGAACTGCGTGACCTGATTACACAGATTCCTGAG
TTGATGATTGATTCCCAAGATGTGAATGGTGAATACCTGAGTCTTCGTGTACGTTTCGCTCTGGTTCGCCGTGAGTCTGG
ATTCATCTCTGGTTTGGTTGCTGTTTTACATGATACGACCGAGCAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CGAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCTCTGTAT
GATCCTGTTGCCCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTAACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGTCCACTCAGTTGGATGTGGAGTTGATTAACTTTACAGCTTTTATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGACGAGAAAAAATATGAACTTGTTAGAGATTACCCAATCAATTCTGTTTGG
ATCGAGATTGATACCGATAAAATGACTCAGGTGATTGATAATATTCTTAACAATGCCATCAAGTATTCACCAGATGGTGG
GAAAATCACTGTCAGCATGAAGACCACAGATGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCGAAGATCTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGAACTGGTCTAGGT
CTGGCCATTGCAAAAGAAATCATCAAACAACACAATGGCTTTATATGGGCCAAAAGTGAATACGGTAAGGGCTCAACCTT
TACCATCGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

88.61

97.773

0.866
  vicK Streptococcus mutans UA159

70.398

89.532

0.63