Detailed information NTG0811321

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: P8191_RS02550
• Genome accession: NZ_CP121250
• Coordinates: 482597..483433 (-)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1044
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 477597..488433

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8191_RS02530 (P8191_02530)	-	477839..478831 (-)	993	WP_010922317.1	D-lactate dehydrogenase	-
P8191_RS02535 (P8191_02535)	-	478846..479391 (-)	546	Protein_507	PTS sugar transporter subunit IIC	-
P8191_RS02540 (P8191_02540)	-	479404..480286 (+)	883	Protein_508	LysR family transcriptional regulator	-
P8191_RS02545 (P8191_02545)	topA	480361..482490 (-)	2130	WP_010922315.1	type I DNA topoisomerase	-
P8191_RS02550 (P8191_02550)	dprA	482597..483433 (-)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
P8191_RS02555 (P8191_02555)	-	483498..484289 (-)	792	WP_011285534.1	ribonuclease HII	-
P8191_RS02560 (P8191_02560)	ylqF	484279..485127 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
P8191_RS02565 (P8191_02565)	-	485346..485786 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
P8191_RS02570 (P8191_02570)	-	485783..486433 (+)	651	WP_002984629.1	hemolysin III family protein	-
P8191_RS02575 (P8191_02575)	-	486550..487461 (+)	912	WP_010922311.1	diacylglycerol kinase family protein	-
P8191_RS02580 (P8191_02580)	-	487511..487879 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=811321 P8191_RS02550 WP_010922314.1 482597..483433(-) (dprA) [Streptococcus pyogenes strain 1044]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=811321 P8191_RS02550 WP_010922314.1 482597..483433(-) (dprA) [Streptococcus pyogenes strain 1044]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367