Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   P3G65_RS10305 Genome accession   NZ_CP120417
Coordinates   1980642..1981859 (+) Length   405 a.a.
NCBI ID   WP_019291567.1    Uniprot ID   A0AAJ2IZW6
Organism   Lactococcus sp. bn62     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1975642..1986859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3G65_RS10275 (P3G65_10270) eeP 1975653..1976900 (-) 1248 WP_019335277.1 RIP metalloprotease RseP Regulator
  P3G65_RS10280 (P3G65_10275) - 1977077..1977871 (-) 795 WP_019291563.1 phosphatidate cytidylyltransferase -
  P3G65_RS10285 (P3G65_10280) - 1977868..1978605 (-) 738 WP_019291564.1 isoprenyl transferase -
  P3G65_RS10290 (P3G65_10285) yajC 1978805..1979140 (-) 336 WP_014025468.1 preprotein translocase subunit YajC -
  P3G65_RS10295 (P3G65_10290) - 1979215..1979862 (-) 648 WP_019291565.1 DNA alkylation repair protein -
  P3G65_RS10300 (P3G65_10295) rlmH 1979859..1980338 (-) 480 WP_019291566.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  P3G65_RS10305 (P3G65_10300) htrA 1980642..1981859 (+) 1218 WP_019291567.1 S1C family serine protease Regulator
  P3G65_RS10310 (P3G65_10305) - 1981956..1982954 (+) 999 WP_019291568.1 glycosyltransferase family 4 protein -
  P3G65_RS10315 (P3G65_10310) - 1982967..1984301 (+) 1335 WP_019291569.1 glycosyltransferase family 4 protein -
  P3G65_RS10320 (P3G65_10315) - 1984352..1984576 (+) 225 WP_003133519.1 DUF1797 family protein -
  P3G65_RS10325 (P3G65_10320) - 1984605..1985654 (-) 1050 WP_019291570.1 BMP family protein -
  P3G65_RS10330 (P3G65_10325) - 1985813..1986562 (-) 750 WP_019291572.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41831.68 Da        Isoelectric Point: 4.8866

>NTDB_id=805574 P3G65_RS10305 WP_019291567.1 1980642..1981859(+) (htrA) [Lactococcus sp. bn62]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=805574 P3G65_RS10305 WP_019291567.1 1980642..1981859(+) (htrA) [Lactococcus sp. bn62]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACAGGCGTAGCCGGGGGTGCTATCGCTCTCGGAGGTAGTGCTATCTA
CCAAAATATGACCAACACGCCGTCATCTAACAACACTTCGGACAATTCTGTAAGTACAGTTAACGTCCAAGTAAATACAG
ATACTACAAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGCGGAGGCGATACAAGTAGCAATGAGAGTAATACGCCACAGCTGGCTGGAGAGGGTTCTGGTGT
TATTTACAAAAAGGATGGCAATACAGCATATATCGTCACCAACTATCACGTTATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCCGGCGGTCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGCAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTGGGTTC
TCCCCTTGGAAGTGAGTATGCAAACTCAGCAACAGAAGGAATTGTTTCAAGTCTAAATCGCAATGTTACACTGCAAAACA
GCCAAGGCCAAACAATTAATGTTAACGCTATTCAAACCGATGCAGCTATTAACCCCGGTAACTCTGGTGGTGCACTCATA
AATATTCAAGGACAAGTCATCGGGATTACCTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCAGTAGTGGTGTCTC
TGTAGAAGGTATGGGATTTGCGATTCCAGCCAATGATGTCGTTAACATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCCCAAAACATGTTAGCTTCACTTAACCTTCCTGAA
AACGTGACTAACGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGCGTGAACCTTCAAAGTACACTTTATAAGTCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAGGCTACTGCGAATATCAAATTGGATAAAACAAGTAGTGATATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(288-396)

PDZ domain (PDZ_2)

(296-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

96.543

0.526
  htrA Streptococcus mutans UA159

56.349

93.333

0.526
  htrA Streptococcus mitis NCTC 12261

52.882

98.519

0.521
  htrA Streptococcus pneumoniae TIGR4

52.632

98.519

0.519
  htrA Streptococcus pneumoniae D39

52.632

98.519

0.519
  htrA Streptococcus pneumoniae Rx1

52.632

98.519

0.519
  htrA Streptococcus pneumoniae R6

52.632

98.519

0.519