Detailed information NTG0802546

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: RG879_RS01135
• Genome accession: NZ_CP134202
• Coordinates: 190148..190609 (+)
• Length: 153 a.a.
• NCBI ID: WP_001878820.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain Alim_agalac_1000
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 185148..195609

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RG879_RS01105	-	186763..187128 (+)	366	WP_000285373.1	DUF1033 family protein	-
RG879_RS01110	comGA	187301..188272 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
RG879_RS01115	comGB	188166..189209 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
RG879_RS01120	comGC/cglC	189206..189535 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
RG879_RS01125	comGD	189510..189923 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
RG879_RS01130	comGE	189895..190194 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
RG879_RS01135	comGF	190148..190609 (+)	462	WP_001878820.1	competence type IV pilus minor pilin ComGF	Machinery gene
RG879_RS01140	comGG	190587..190958 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
RG879_RS01145	comGH	191073..192047 (+)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
RG879_RS01150	-	192079..193272 (+)	1194	WP_000047534.1	acetate kinase	-
RG879_RS01155	-	193424..193630 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
RG879_RS01160	-	193689..193826 (+)	138	WP_001865900.1	hypothetical protein	-
RG879_RS01165	-	193867..194322 (+)	456	WP_000905673.1	hypothetical protein	-
RG879_RS01170	-	194391..195056 (+)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17874.95 Da
• Isoelectric Point: 10.0299

>NTDB_id=802546 RG879_RS01135 WP_001878820.1 190148..190609(+) (comGF) [Streptococcus agalactiae strain Alim_agalac_1000]
MKIIRKFCTYQKLRVKAFTLLKCLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=802546 RG879_RS01135 WP_001878820.1 190148..190609(+) (comGF) [Streptococcus agalactiae strain Alim_agalac_1000]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAAAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.183	92.81	0.438
comGF	Streptococcus mutans UA140	47.183	92.81	0.438
comGF/cglF	Streptococcus pneumoniae Rx1	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae D39	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae R6	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae TIGR4	42.446	90.85	0.386
comGF/cglF	Streptococcus mitis SK321	43.284	87.582	0.379
comGF/cglF	Streptococcus mitis NCTC 12261	42.537	87.582	0.373
comGF	Lactococcus lactis subsp. cremoris KW2	40	91.503	0.366